Immunosuppressant Analogs in Neuroprotection

I: Immunosuppressants, Neurologic Disorders, and Neuroprotection.- 1 • Introduction: Immunosuppressants as Neuroprotective Agents.- II: Immunosuppressants and Parkinson’s Disease.- 2 • Cyclosporin-Mediated Amelioration of Degeneration of Dopaminergic Neurons in Experimental Models of Parkinsonism.- 3 • Immunophilin Ligands and Dopamine Neurons: Specific Effects in Culture and In Vivo.- 4 • Effects of Neuroimmunophilin Ligands on Parkinson’s Disease and Cognition.- 5 • Improved Survival of Grafted Dopamine Neurons by Calcineurin Inhibitors.- 6 • Possible Mechanisms Underlying the Protective Action of Immunosuppressants Against Parkinson’s Disease: The Mitochondrial Permeability Transition Pore Hypothesis.- III: Immunosuppressants and other Age-Related Disorders.- 7 • Immunosuppressants and Alzheimer’s Disease.- 8 • Cyclosporin A Protects Striatal Neurons from Mitochondrial Dysfunction: Implications for Huntington’s Disease.- IV: Immunosuppressants, Stroke, and Traumatic Brain Injury.- 9 • Cyclosporin A Protects Mitochondria in an In Vitro Model of Hypoxia/Reperfusion Injury.- 10 • Protective Effect of Cyclosporin A on Glial Activation and White Matter Alterations Induced by Chronic Cerebral Hypoperfusion.- 11 • Blockade of Late-Onset Reduction of Muscarinic Acetylcholine Receptors by Immunosuppressants in Forebrain Ischemia.- 12 • The Role of Immunophilins in Focal Cerebral Ischemia: Evidence of Neuroprotection by FK506.- 13 • Immunosuppressants in Traumatic Brain Injury.- V: Immunosuppressants and Spinal Cord Injury.- 14 • Inhibition of Lipid Peroxidation by Cyclosporin After Spinal Cord Injury in Rats.- 15 • Axonal Regeneration in Cyclosporin A-Treated Rats Submitted to Transverse Section of the Spinal Cord.- VI:Immunosuppressants and Sciatic Nerve Injury.- 16 • Neuroimmunophilin Ligands Accelerate and Promote Nerve Regeneration in the Rat Peripheral Nerve and Spinal Cord: Role of the Steroid Receptor—FKBP52 Complex.- 17 • Neuroimmunophilin Ligands Stimulate Recovery of Injured Sciatic Nerves.- VII: Immunosuppressants and other Disorders of the Central Nervous System.- 18 • Cyclosporin A Prolongs Survival of SOD1 Mutant Mice and Implicates Mitochondrial Permeability Transition in Amyotrophic Lateral Sclerosis.- 19 • Psychological Effects of Cyclosporin A.

Forerword by Solomon H. Snyder