Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications
Springer (Verlag)
978-94-007-7358-5 (ISBN)
Preface. Part I Introduction.- Overview of the Carbonic Anhydrase Field.- Part II Carbonic Anhydrases: Ancient but Relevant. Physiological Functions of the Alpha Class of Carbonic Anhydrases.- Catalytic Mechanism of α-Class Carbonic Anhydrases: CO2 Hydration and Proton Transfer.- Structure and Catalytic Mechanism of b-Carbonic Anhydrases.- Prokaryotic Carbonic Anhydrases of Earth’s Environment.- Carboxysomal Carbonic Anhydrases.- Carbonic Anhydrases and their Interplay with Acid/base-coupled Membrane Transporters.- Carbonic Anhydrase Related Proteins: Molecular Biology and Evolution.- Membrane Associated Carbonic Anhydrase IV (CA IV): A Personal and Historical Perspective.- Carbonic Anhydrase Expression in Kidney and Renal Cancer: Implications for Diagnosis and Treatment.- Carbonic Anhydrase IX: Regulation and Role in Cancer.- Carbonic Anhydrase IX as an Imaging and Therapeutic Target for Tumors and Metastases.- Carbonic Anhydrase IX (CAIX) as a Mediator of Hypoxia-induced Stress Response in Cancer Cells.- Carbonic Anhydrases and Brain pH in the Control of Neruronal Excitability.- Carbonic Anhydrase Inhibitors: Drug Design.- Natural Products that Inhibit Carbonic Anhydrases.- Glaucoma and the Application of Carbonic Anhydrase Inhibitors.- Carbonic Anhydrase Inhibitors and High Altitude Illnesses.- Thermal-Stable Carbonic Anhydrases: A Structural Overview.- Carbonic Anhydrases in Industrial Applications. Index.
Erscheint lt. Verlag | 5.11.2013 |
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Reihe/Serie | Subcellular Biochemistry ; 75 |
Zusatzinfo | 37 Illustrations, color; 38 Illustrations, black and white; IX, 430 p. 75 illus., 37 illus. in color. |
Verlagsort | Dordrecht |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Biochemie | |
ISBN-10 | 94-007-7358-7 / 9400773587 |
ISBN-13 | 978-94-007-7358-5 / 9789400773585 |
Zustand | Neuware |
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