Cellular Mechanisms in Airways Inflammation

Airways disease encompasses a broad range of pathologies including Bronchial Asthma, Rhinitis, Chronic Obstructive Pulmonary Disease, Bronchitis, Acute Bronchiolitis, Emphysema and Fibrosing Alveolitis. A characteristic feature of these diseases is the recruitment and activation of numerous cell types. Airways inflammation contributes to the pathophysiology of airways disease...

Contents. List of Contributors. Preface. Peter K. Jeffery: Pathological spectrum of airway inflammation. Gianni Marone, Anna Ciccarelli, Giuseppe Spadaro and Anna Maria Onorati: Role of basophils in airways inflammation. Paolo Gresele and Roberta Vezza: Platelets. Moira Whyte: Neutrophils. Anthony J. Coyle, Jose Carlos Gutierrez-Ramos: Eosinophils in asthma. Ian A. Akers, Robin J. McAnulty and Geoffrey J. Laurent: Fibroblasts and myofibroblasts. Elaine Lee and Stephen A. Kilfeather: Airway macrophages and dendritic cells. Anne Burke-Gaffney and Paul G. Hellewell: Contribution of endothelial cells to airway inflammation. Jagdish Laxman Devalia, Jia Hua Wang and Robert James Davies: Airway epithelial cells. Alastair G. Stewart, Darren J. Fernandes, Valentina Kalafatis, Aurora Messina, Claire E. Ravenhall, Ross Vlahos and Kai-Feng Xu: Airway smooth muscle cells. K. H. Banner, D. Spina and C. P. Page: Drugs that reduce airways inflammation. D. M. Kemeny and B. J. O`Connor: T cells in the lung. Index.