Modern Therapeutics in Rheumatic Diseases

I. Rheumatoid Arthritis.- 1 New Treatment Opportunities for Rheumatoid Arthritis.- 2 Genetic Influences on Treatment Response in Rheumatoid Arthritis.- 3 Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Rheumatoid Arthritis.- 4 Additional Considerations on the Use of Nonsteroidal Anti-Inflammatory Drugs.- 5 Glucocorticoid Therapy in Rheumatoid Arthritis.- 6 Anti-Tumor Necrosis Factor Agents.- 7 Interleukin-1 Receptor Antagonist Treatment in Rheumatoid Arthritis.- 8 Leflunomide: An Immunomodulatory Drug for the Treatment of Rheumatoid Arthritis.- 9 Matrix Metalloproteinase Inhibitors as Therapies for Rheumatoid Arthritis.- 10 Combination Disease-Modifying Anti-Rheumatic Drug (DMARD) Therapy.- 11 Experimental Therapeutics for Rheumatoid Arthritis.- II. Osteoarthritis.- 12 Slow-Acting Drugs for the Treatment of Osteoarthritis.- 13 Intra-Articular Therapy in Osteoarthritis.- 14 Promoting Articular Cartilage Repair.- 15 Using Molecular Markers to Monitor Osteoarthritis.- 16 New Therapeutic Targets for Osteoarthritis: The Rewards of Research.- 17 Recent Developments in the Therapy of Osteoarthritis.- III. Systemic Autoimmune Diseases.- 18 Treatment of Systemic Lupus Erythematosus.- 19 Treatment of the Antiphospholipid Syndrome.- 20 Treatment of Systemic Lupus Erythematosus by Blocking T-Cell Costimulation.- 21 Current Management of Systemic Sclerosis.- 22 Sjögren’s Syndrome.- 23 Mixed Connective Tissue Disease.- 24 Vasculitis.- 25 Treatment of Juvenile Rheumatoid Arthritis.- 26 Treatment of Inflammatory Myopathies.- 27 Psoriatic Arthritis.- 28 Complement Inhibitors in Rheumatic Diseases.- 29 Hematopoietic Stem Cell Transplantation of Autoimmune Disease.- IV. Gene Therapy in Rheumatic Diseases.- 30 Vectors for Gene Delivery.- 31 Gene Targeting of Cytokines and theMitogen-Activated Protein Kinase Pathways in Human Rheumatoid Synovium Using the Severe Combined Immunodeficiency Mouse Model.- 32 Retroviral Transduction of Antigen-Specific CD4+ T Cells for Local Delivery of Regulatory Molecules.- 33 Gene Transfer to Lymphocytes Targeting Cartilaginous Collagen Type II.- 34 Gene Therapy in Murine Arthritis: Cytokine-Directed Targeting.- 35 Modulation of the IKB Kinase/Nuclear Factor-KB Pathway by Gene Therapy.- 36 Regulation of Apoptosis in Rheumatoid Synoviocytes.- 37 Gene Therapy for Arthritis: Conception, Consolidation, and Clinical Trial.- V. Other Rheumatic Disorders.- 38 Recent Advances in the Pharmacotherapy of Spondyloarthropathies.- 39 Modern Therapy of Crystal Arthropathies.- 40 Treatment of Musculoskeletal Infections.