Principles & Practice of Assisted Reproductive Technology (3 Vols)

Kamini Rao DGO DORCP DCh FRCOG (UK) MCh (UK) FICOG PGDMLE (Law) Milann Infertility Centre, Jayanagar, Bangalore, Karnataka, India  

Volume 1: Infertility

SECTION 1: PHYSIOLOGY





Anatomy and physiology of male & female reproductive system
Ooogenesis and Folliculogenesis
Physiology of Menstrual Cycle
Human spermatozoa – Production and Migration
The Human Sperm : Its Contribution to Fertilization and embryogenesis
Endometrial receptivity
Embryo maternal dialogue and Implantation


 



SECTION 2: REPRODUCTIVE ENDOCRINOLOGY





Hyperprolactinemia and Thyroid disorders
Hirsutism
Fertility treatment in Primary and Secondary Amenorrhoea
Luteal Phase defect
Anovulatory infertility


 



SECTION 3: MALE INFERTILITY





Etiology and Pathophysiology of male infertility
Clinical and Endocrinological evaluation of the infertile male
The Microbiology of semen and Infections of the Male Genito urinary tract
Sexual Dysfunction
Cytogenetics of male infertility
Role of sonography and doppler in male infertility
Varicocele and its role in male infertility
Medical Management of male infertility
Management of Azoospermia
Sperm Retrieval techniques


 



SECTION 4: GENERAL OVERVIEW





Patient selection and management
Immunology in Infertility
Environmental factors affecting fertility
Declining fertility


 



SECTION 5: FEMALE FACTOR INFERTILITY





Evaluation of infertile female
Uterine and Cervical factors in Infertility
Tubal factors in Infertility
Role of HSG and SSG in evaluating the fallopian tubes
Infections and infertility
Tuberculosis and Infertility
Transvaginal sonography and Doppler in female Infertility
Endoscopy in Infertility
Assessment of ovarian reserve
Endometriosis and Infertility
Role of fibroids in infertility
Reconstructive Surgeries enhancing infertility
Obesity and Infertility
Unexplained Infertility
Fertility preservation in female patients


 



SECTION 6: OVULATION INDUCTION





Drugs for Controlled ovarian stimulation
Super Ovulation Strategies in Assisted conception
GnRH Agonists
GnRH Antagonists
Monitoring of ovulation induction
Ovulation trigger
Individualized stimulation protocol
Mild stimulation protocols
Role of LH in ovarian stimulation
Progesterone in ovarian stimulation
Prognosticating and Optimizing IVF outcome
Luteal phase support


 



SECTION 7: INTRAUTERINE INSEMINATION





Intrauterine Insemination
Optimizing success in IUI


 



SECTION 8: ASSISTED REPRODUCTIVE TECHNIQUES





Anaesthesia and IVF
Oocyte retrieval
Embryo Transfer


 



SECTION 9: DILEMMAS IN ART





Treatment strategies in poor responders
Recurrent Implantation Failure
Empty Follicle Syndrome
Single Embryo Transfer
Role of Aneuploidy screening in pre implantation embryos
Epigenetics and AR


 



SECTION 10: COMPLICATIONS OF ART





Ovarian Hyperstimulation Syndrome
Ectopic Pregnancy
Latrogenic multiple pregnancy
Fetal Reduction
Oncogenic risks related to ART


 



SECTION 11: THIRD PARTY REPRODUCTION





Oocyte and Embryo Donation
Oocyte Sharing Programmes
Surrogacy
Challenges faced in setting up a Surrogate house within the ICMR guidelines
Adoption


 



SECTION 12: MISCELLANEOUS





Batch IVF
Alternatives of ART
Endometrial preparation in FET cycles


 



SECTION 13: OUTCOME FOLLOWING ART





Obstetric outcome following ART
Outcome of children born through ART


 



SECTION 14: GRIEF COUNSELLING



 



SECTION 15: ETHICAL AND LEGAL ISSUES





Ethical legal and social issues of modern ART treatment


 



SECTION 16: FUTURE CLINICAL APPLICATIONS





Endometrial stem cells and reproduction


 



Volume 2: IVF and Related Procedures



SECTION 1: ANDROLOGY





Semen Analysis in 21st Century Medicine—A Paradigm Shift
Sperm Chromatin Assessment
Ejaculatory Failure
Sperm Preparation in Assisted Conception: Laboratory Techniques
Semen Banking


 



SECTION 2: EMBRYOLOGY





History of In Vitro Fertilization
In Vitro Fertilization and Embryo Transfer
Intracytoplasmic Sperm Injection
Analysis of Fertilization
Morphological Assessment of Oocyte and Embryo
Blastocyst Culture and Transfer 
Advantages and Disadvantages of Embryo Transfer on Day 2, Day 3 and Blastocyst Stage
Embryo Transfer Techniques
Cryopreservation of Oocytes and Embryos by Slow Freezing Method
Oocyte Vitrification
Vitrification


 



SECTION 3: ADVANCES IN ASSISTED REPRODUCTVE TECHNOLOGIES





Assisted Hatching
Embryo Biopsy for Preimplantation Genetic Diagnosis
In Vitro Maturation of Oocytes: A Practical Approach
Ovarian Tissue Cryopreservation
Time Lapse Video for Assessing the Embryos
Polarization Microscopy
OMICS
IMSI and its Clinical Significance
Microfluidics in ART


 



SECTION 4: ETHICAL AND LEGAL ISSUES





Certification and Accreditation-Relevance to an IVF Center
Accreditation of an ART Laboratory


 



SECTION 5: LABORATORY MANAGEMENT





Setting-up an ART Laboratory
Quality Control of IVF Laboratory
Culture Systems
Micromanipulators
Troubleshooting in ART


 



Volume 3: Atlas of Embryology





Oocyte Cumulus Complex Evaluation
Oocyte Nuclear Maturity Evaluation
Oocyte Dysmorphisms
The Sperm
Normal Embryo Development
Embryo Scoring
In Vitro Fertilization/Intracytoplasmic Sperm Injection
Advanced Techniques
Cryopreservation
Assisted Reproductive Technology Lab Setting