Oxford Textbook of Rheumatology

Richard A Watts, University of East Anglia and Ipswich Hospital NHS Trust, UK, Philip Conaghan, University of Leeds and Leeds Teaching Hospitals NHS Trust, UK, Chris Denton, University College London, UK, Helen Foster, University of Newcastle, UK, John Issacs, University of Newcastle, UK, Ulf Muller-Ladner, Justus-Liebig Universitat Giessen, Germany

SECTION 1 CLINICAL PRESENTATIONS OF RHEUMATIC DISEASE IN DIFFERENT AGE GROUPS
1. The child patient
2. Young people and transitional care in rheumatology
3. The adult patient
4. The elderly patient
5. Principles of clinical examination in children
6. Principles of clinical examination in adults

SECTION 2 COMMON CLINICAL PROBLEMS OF RHEUMATIC DISEASE
7. Monoarticular disease
8. Oligoarticular disease
9. Polyarticular disease
10. The systemically ill patient
11. Spinal pain
12. Pain and Fatigue
13. The limping child
14. The systemically unwell child
15. Primary care presentation

SECTION 3 CLINICAL PRESENTATIONS: VIEWS FROM DIFFERENT PERSPECTIVES
16. Obstetrics and pregnancy
17. The skin
18. The nervous system
19. The cardiovascular system
20. The respiratory system
21. The gastrointestinal system
22. The neuroendocrine system
23. Malignancy
24. The eye
25. The kidney
26. Psychology

SECTION 4 THE IMPACT OF RHEUMATIC DISEASE
27. Epidemiology of rheumatic diseases
28. Assessment of rheumatic disease
29. Outcomes
30. Design of clinical trials in rheumatology
31. Health economics
32. Co-morbidities of rheumatic disease
33. Social aspects (work)
34. Biologics registries
35. Outcomes of paediatric rheumatic disease
36. Assessment of paediatric rheumatic disease

SECTION 5 GENETICS AND ENVIRONMENT
37. Basics of genetics
38. Environment
39. Epigenetics
40. Genetics of rheumatoid arthritis
41. Genetics of Spondyloarthropathies
42. Genetics of Connective tissue diseases
43. Genetics of juvenile rheumatic disease
44. Genetics of osteoarthritis
45. Genetics of chronic musculoskeletal pain

SECTION 6 TISSUE IN HEALTH AND DISEASE
46. The normal functional anatomy of joints
47. Measuring movement and gait
48. Innate vs. acquired immunity
49. T Cellular side of acquired immunity (T cells)
50. Cellular side of acquired immunity (B cells)
51. Fibroblasts and mesenchymal cells
52. Synovial pathology
53. Bone turnover
54. Enthesitis
55. Skeletal muscle physiology and damage
56. Joint biochemistry
57. Vascular biology
58. Acute phase responses and adipocytokines
59. Pain neurophysiology
60. The pathogenesis of juvenile idiopathic arthritis

SECTION 7 PRACTICAL INVESTIGATION OF RHEUMATIC DISEASE
61. Haematology
62. Biochemical investigation of rheumatic diseases
63. Auto-immune serology
64. Complement
65. Limb anatomy and medical imaging
66. Radiographic imaging
67. Ultrasound
68. Magnetic resonance imaging
69. Computed tomography
70. Nuclear medicine
71. Imaging in children
72. Assessment of synovial joint fluid
73. Cardiopulmonary investigation
74. Electrophysiology

SECTION 8 MANAGEMENT OF RHEUMATIC DISEASE
75. Patient education
76. Multidisciplinary treatment
77. Cyclooxygenase inhibitors
78. Analgesics
79. Glucocorticoids
80. Immunosuppressants
81. Signalling pathway inhibitors
82. Anti-cytokine biologics
83. Cellular therapies
84. Biologics in paediatric rheumatic diseases
85. Stem cell therapies
86. Tissue engineering
87. Injection therapy
88. Diet and obesity
89. Alternative therapies
90. Principles of upper limb surgery
91. Principles of lower limb surgery
92. Principles of spine surgery
93. Perioperative management of immunosuppression
94. Vaccination in immunocompromised adults
95. Vaccination in immunocompromised children
96. Principles of management of juvenile idiopathic arthritis
97. Anti-rheumatic drugs in pregnancy and lactation

SECTION 9 INFECTION IN RHEUMATIC DISEASE
98. Septic arthritis in adults
99. Bone and joint infections in children
100. Osteomyelitis
101. Lyme disease
102. Viral arthritis
103. Mycobacterial diseases
104. Brucellar arthritis
105. Parasitic involvement
106. Fungal arthritis
107. Opportunistic infection
108. Rheumatic fever

SECTION 10 RHEUMATOID ARTHRITIS
109. Pathogenesis of rheumatoid arthritis
110. Rheumatoid arthritis - diagnosis
111. Rheumatoid arthritis - clinical features
112. Rheumatoid arthritis - management

SECTION 11 SPONDYLOARTHROPATHIES
113. Ankylosing spondylitis
114. Psoriatic arthritis
115. Reactive arthritis and enteropathic arthropathy

SECTION 12 ARTHROPATHIES PRIMARILY OCCURING IN CHILDHOOD
116. Juvenile idiopathic arthritis

SECTION 13 SYSTEMIC LUPUS ERYTHEMATOSUS
117. Systemic lupus erythematosus - clinical features and aetiopathogenesis
118. Systemic lupus erythematosus - management
119. Paediatric onset systemic lupus erythematosus
120. The antiphospholipid antibody syndrome

SECTION 14 SCLERODERMA
121. Systemic sclerosis
122. Paediatric scleroderma and related disorders
123. Nephrogenic systemic fibrosis

SECTION 15 MYOSITIS
124. Polymyositis and dermatomyositis in adults
125. Paediatric polymyositis and dermatomyositis
126. Non-inflammatory myopathies

SECTION 16 SJOGREN'S SYNDROME
127. Sjogren's syndrome: clinical features
128. Sjogren's syndrome: management

SECTION 17 OVERLAP/UNDIFFERENTIATED SYNDROME
129. Overlap/undifferentiated syndrome

SECTION 18 VASCULITIS
130. Classification and diagnosis
131. Clinical features of primary ANCA-associated vasculitis
132. Treatment of ANCA vasculitis
133. Large vessel vasculitis
134. Polymyalgia rheumatica
135. Behcet's syndrome
136. Paediatric vasculitis
137. Miscellaneous vasculitides

SECTION 19 OSTEOARTHRITIS
138. Pathogenesis of osteoarthritis
139. Clinical features of osteoarthritis
140. Osteoarthritis management

SECTION 20 CRYSTAL ARTHROPATHIES
141. Gout
142. Calcium pyrophosphate crystal deposition (CPPD)

SECTION 21 DISEASES OF BONE AND CARTILAGE
143. Osteoporosis
144. Paget's disease of bone
145. Paediatric metabolic bone disease
146. Disorders of bone mineralisation: Osteomalacia
147. Bone Tumours
148. Avascular necrosis
149. Renal osteodystrophy
150. Skeletal dysplasias

SECTION 22 REGIONAL RHEUMATIC DISEASE
151. Shoulder
152. Elbow
153. Forearm, hand and wrist
154. Pelvis, groin and thigh
155. Knee
156. Foot and ankle
157. Cervical and lumbar spine
158. Childhood regional conditions
159. Hypermobility syndromes
160. Fibromyalgia and chronic widespread pain syndromes: adult onset
161. Fibromyalgia and chronic widespread pain syndromes: adult onset
162. Sports and exercise injuries

SECTION 23 MISCELLANEOUS CONDITIONS
163. Amyloidosis
164. Auto-inflammatory diseases
165. Panniculitides
166. Neutrophilic dermatoses
167. Sarcoidosis
168. Macrophage activation syndrome
169. Multicentric reticulohistiocytosis
170. Inherited metabolic diseases
171. The rheumatological manifestations of endocrine disorders
172. Haemoglobinopathies
173. Haemochromatosis