Brain Tumor Immunotherapy

Part I. Introduction to the Disease. Neuropathology and Molecular Pathogenesis of Primary Brain Tumors, Paul S. Mischel and Harry V. Vinters. Epidemiology of Primary Brain Tumors, Susan Preston-Martin, Faith Davis, and Roberta McKean-Cowdin. Current Therapy for Primary Brain Tumors, John M. Duff, Pierre-Yves Dietrich, and Nicolas de Tribolet. Part II. Introduction to Immunotherapy of Brain Tumors. Immunostimulation and Immunomodulation of Brain Tumors, Victor C. K. Tse and Frances K. Conley. Biological Principles of Brain Tumor Immunotherapy, Amy B. Heimberger, Darell D. Bigner, and John H. Sampson. Part III. Adoptive Cellular Immunotherapy of Brain Tumors. Systemic T-Cell Immunotherapy for Brain Tumors, Gregory E. Plautz and Suyu Shu. Cytotoxic T-Lymphocytes Reactive to Patient Major Histocompatibility Complex Proteins for Therapy of Brain Tumors, Carol A. Kruse and David Rubinstein. Autologous Vaccine and Adoptive Cellular Immunotherapy as Treatment for Brain Tumors, Gary W. Wood and Frank P. Holladay. Part IV. Antibody-Mediated Immunotherapy of Brain Tumors. Anti-Idiotype Immunotherapy Strategies for Brain Tumors, Nai-Kong V. Cheung. Radiolabeled Antibodies for Therapy of Brain Tumors, Carol J. Wikstrand, Michael R. Zalutsky, and Darell D. Bigner. Immunotoxin Therapy of Brain Tumors, Walter A. Hall. Antibodies to Adhesion Molecules for Immunotherapy of Brain Tumors, S. Ather Enam. Part V. Tumor Vaccines and Other Strategies. Cytokine-Based Immuno-Gene Therapy for Brain Tumors, Roberta P. Glick, Terry Lichtor, and Edward P. Cohen. Downregulation of Transforming Growth Factor b as Therapeutic Approach for Brain Tumors, Habib Fakhrai, Svetlana Gramatikova, and Rohangiz Safaei. Dendritic Cell Immunotherapy for Brain Tumors, Stéphane Vandenabeele, Linda M. Liau, andDavid Ashley. Death Ligand/Death Receptor-Mediated Apoptosis for Treatment of Brain Tumors, Wilfried Roth and Michael Weller. Combining Radiation Therapy with Immunotherapy for Treatment of Brain Tumors,William H. McBride. Index.