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Airways and Vascular Remodelling in Asthma and Cardiovascular Disease

Implications for Therapeutic Intervention

Clive Page, Judith Black (Herausgeber)

Buch | Hardcover
189 Seiten
1994
Academic Press Inc (Verlag)
978-0-12-543540-6 (ISBN)
54,85 inkl. MwSt
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This text compares and contrasts research progress made in the areas of vascular disease and asthma, including the current understanding of the pathophysiology involved in these diseases and the results of multi-centre trials.
Vascular diseases and asthma are two common diseases associated with considerable morbidity and mortality. Both are chronic, each has an inflammatory component, both are accompanied by remodelling of hollow tubes and both are amenable to early intervention. This book compares and contrasts research progress made in each area, including our current understanding of the pathophysiology involved and the results of large-scale multicentre trials.

Professor Clive P. Page, BSc PhD OBE HonFBPhS is a Professor of Pharmacology, King’s College London and Director of the Sackler Institute of Pulmonary Pharmacology, King’s College London. Clive’s main research interests are in the pharmacology of inflammation and respiratory disease and he has published over 250 scientific papers. Clive was the co-founder and previous Chairman of the Board of Verona Pharma plc, an AIM listed Company developing new drugs for the treatment of Respiratory Diseases. He is a Non Executive Director of and on boards of several companies. He was awarded the Society of Biology President’s Medal in 2012 for an outstanding contribution to the life sciences over the previous year. He is a Fellow of the Royal Society of Biology and an Honorary Fellow and President Elect of the British Pharmacological Society. In 2017, Clive was awarded an OBE for Services to Pharmacology.

P.K. Jefferey, Structural Changes in Asthma.
T. Cocks, Changes in Vascular Reactivity in Artherogenesis: Markers of Endothial Cell Dysfunction Associated with Initiation of the Disease.
J.H. Campbell and G.R. Campbell, Vascular Smooth Muscle in Culture and its Relevance to the Study of Arthrogenesis.
V. Lindner, In Vivo Investigations of Vascular Smooth Muscle Remodelling.
M.J. Karnovsky and E.R. Edelman, Heparin/Heparan Sulphate Regulation of Vascular Smooth Muscle Cell Behaviour.
M.I. Kotlikoff, Regulation of Cytoplasmic Calcium in Airway Smooth Muscle Cells: Implications for Growth and Contractility.
J.G. Martin, Animal Studies with Drugs Affecting Airway Smooth Muscle Thickening.
M. Okazawa, P.D. Pare, J.C. Hogg, and R.K. Lambert, Mechanical Consequences of Remodelling of the Airway Wall.
A.J. Woolcock and J.K. Peat, Is Asthma a Reversible Disease?
L.A. Laitinen and A. Laitinen, Anti-Inflammatory Therapy of Asthma: Corticosteroids.
P. Konig, Anti-Inflammatory Therapy of Asthma: Non-Steroid Disease Modifying Agents.
P. Gresele, Design of Large Multicentre Therapeutic Trials.
The Relevance of the Cardiovascular Experience to the Design of Long Term Anti-Asthma Trials.
Discussion Section.
Subject Index.

Erscheint lt. Verlag 8.8.1994
Verlagsort San Diego
Sprache englisch
Maße 152 x 229 mm
Gewicht 480 g
Themenwelt Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizinische Fachgebiete Innere Medizin Pneumologie
ISBN-10 0-12-543540-1 / 0125435401
ISBN-13 978-0-12-543540-6 / 9780125435406
Zustand Neuware
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