Handbook of Obesity, Two-Volume Set

George A. Bray, Claude Bouchard

VOLUME ONE. History, Definitions, and Prevalence. Obesity Has Always Been with Us: An Historical Introduction. Measurement of Total Adiposity, Regional Fat Depots, and Ectopic Fat. Anthropometric Indicators in Relation to the Gold Standards. Worldwide Prevalence of Obesity in Adults. Prevalence and Consequences of Pediatric Obesity. Obesity in Older Adults in the United States. Gender, Ethnic, and Geographic Variation in Adiposity. Biological Determinants of Obesity. Genetic Component to Obesity: Evidence from Genetic Epidemiology. Genes and the Predisposition to Obesity. Epigenetic Mechanisms in Obesity. Fetal and Early Postnatal Life Determinants of Adiposity. Animal Models of Obesity: Perspectives on Evolution of Strategies for Their Development and Analysis of Their Phenotypes. Animal Models of Obesity: Nonhuman Primates. CNS Regulation of Energy Balance. Gastrointestinal Regulation of Energy Balance. Gut Microbiome and Obesity. Sympathetic Nervous System and Endocrine Determinants of Energy Balance. Insulin Resistance and Obesity. White and Brown Adipose Tissue Development. Adipose Tissue Metabolism, Adipokines, and Obesity. Visceral Adipose Tissue and Ectopic Fat Deposition. Skeletal Muscle Metabolism and Obesity. Mitochondrial Bioenergetic Aspects of Obesity and Weight Loss. Resting Metabolic Rate, Thermic Effect of Food, and Obesity. Energy Cost of Exercise, Postexercise Metabolic Rates, and Obesity. Energy Partitioning, Substrate Oxidation Rates, and Obesity. Viral Infections and Adiposity. Behavioral Determinants of Obesity. Obesity: Influence of the Food Environment on Ingestive Behaviors. Obesity and Related Eating Disorders. Tobacco Use, Smoking Cessation, and Obesity. Breastfeeding and Later Obesity. Beverages and Obesity: Biology, History, Trends. Sedentary Time and Obesity. Occupational Work and Obesity. Leisure-Time Physical Activity and Obesity. Sustained Short Sleep and Risk of Obesity: Evidence in Children and Adults. Environmental, Social, and Cultural Determinants of Obesity. Role of Agriculture and the Food Industry in America’s Obesity. Transportation Policies and Obesity. Urban Environment, Building Design, and Obesity. Social and Economic Determinants of Obesity. Influence of Culture on Obesity. Bias, Discrimination, and Obesity. Environmental Chemicals and Obesity. Economic Costs of Obesity. Consequences of Obesity. Obesity and Mortality Rates. Obesity and Heart Disease. Obesity and Hypertension. Obesity and Lipoprotein Metabolism. Obesity and Type Diabetes. Obesity and Metabolic Syndrome. Obesity and Cancer: Clinical Epidemiology. Inflammatory Causes of Obesity and Metabolic Diseases. Obesity and Gallbladder Disease. Obesity and Liver: Cell Death, Compensatory Growth, and Repair of Damage. Obesity, Lung Function, and Lung Disease. Obesity, Arthritis, and Gout. Obesity and Mental Health. Obesity and Health-Related Quality of Life. Obesity and Pregnancy Outcomes. Obesity, an Inactive Lifestyle and Low Fitness: The Most Unhealthy Combination. Index. VOLUME TWO. Prevention of Obesity. Dietary Changes in Human Evolution: Implications for Prevention of Obesity; Prevention in Adults; Prevention of Obesity in Childhood and Adolescence; Reengineering the Built Environment: Progress in Schools, Work Sites, Neighborhoods, and Parks; Obesity and Evolution: Implications for Prevention of Type 2 Diabetes; Evaluation of the Overweight or Obese Patient. Classification and Evaluation of the Overweight Patient; Waist Girth: A Critical Evaluation of Usefulness; Genetic Evaluation of Patients with Syndromic and Nonsyndromic Obesity; Impact of Voluntary Weight Loss on Morbidity and Mortality; Obesity and the Primary Care Physician; Medical Treatment of Obesity and Weight Management Issues in the Treatment of Obesity: Behavior, Diet, Exercise and Medications. Behavioral Approaches to the Treatment of Obesity; Preventing Weight Regain after Weight Loss; Strategies to Reduce Calories in Food; Diet Composition and Weight Loss; Dietary Protein and Weight Management; Exercise and Weight Management; Drugs That Cause Weight Gain and Clinical Alternatives to Their Use; Sibutramine, Phentermine, and Diethylpropion: Sympathomimetic Drugs in the Management of Obesity; Drugs That Modify Fat Absorption and Alter Metabolism; Serotonin Receptor Modulation in the Treatment of Obesity; Combination Therapy: Topiramate and Phentermine; Bupropion plus Naltrexone (Contrave); Glucagon-Like Peptide- Agonists and Weight Regulation; Brown Adipose Tissue as a Target; Herbal and Alternative Approaches to Obesity; Is There a Future for Gene Therapy in Obesity? Special Issues in Treatment of Pediatric Obesity; Prevention and Management of Dyslipidemia, Hyperglycemia, and the Metabolic Syndrome in Obese Patients; Surgery. Surgical Procedures in the Treatment of Obesity and Its Comorbidities; Swedish Obese Subjects, SOS; Laparoscopic Adjustable Gastric Banding; Evolving Surgical Therapy for Obesity; Liposuction and Obesity; Mechanisms Underlying the Endocrine Management of Postbariatric Surgical Patients; Epilogue. Cost-Effectiveness of Obesity Prevention and Treatment; Government’s Evolving Role: Nutrition, Education, Regulation, Monitoring, and Research; Index.