Minimal Residual Disease in Melanoma

This volume comprises the proceedings of the First International Symposium on Minimal Residual Disease in Melanoma, held in Homburg/Saar, Germany in September 1999. Containing contributions by 24 renowned experts, the book covers all aspects of diagnosis and treatment of micrometastatic disease in melanoma. The topics include: biology of micrometastases and advanced methods for detection; detection of residual melanoma cells in the peripheral blood and bone marrow; detection of minimal residual disease in sentinel nodes; early recognition and monitoring by serological markers; clinical relevance of micrometastasis detection; therapeutic strategies to deal with residual melanoma cells. TOC:Biology of micrometastases and advanced methods for detection.- Detection of residual melanoma cells in the peripheral blood and bone marrow.- Detection of minimal residual disease in sentinel nodes.- Early recognition and monitoring by serological markers.- Clinical relevance of micrometastasis detection.- Therapeutic strategies against residual melanoma cells.