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Adalat® in the Asian Pacific Region

David T. Kelly (Herausgeber)

Buch | Softcover

XIV, 138 Seiten

1989
Springer Berlin (Verlag)
978-3-540-51388-9 (ISBN)

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These are the proceedings of the third Asian Pacific Adalat Symposium. The first was held in Tokyo in 1982 and the second in Sydney in 1985. We were honoured that the late Dr. Sukaman and his colleagues were able to host this third symposium in Jakarta. This meeting was designed to contribute to and to promote international collaboration in cardiovascular research, and to help promote further knowledge and understanding about the treatment of vascular disease in the Asian Pacific area. Nifedipine was originally investigated in the mid-1960s by Prof. Fleckenstein. His first results showed this drug was a powerful calcium antagonist which altered excitation contraction. At this time, there was a rapid development of knowledge about the pathophysiology of ischaemic heart disease, and thus the important pharmacological work on calcium antagonists such as nifedipine paralleled and complimented the newer understanding of coronary physiology in man. In a short time most therapy was designed to reduce myocardial oxygen consumption and demand.

Ischemic Heart Disease.- Study on the Clinical Effectiveness of Adalat L Tablet for Angina Pectoris: A Double-blind Study with Adalat as a Reference Drug.- Nifedipine-induced Reperfusion in Stable Angina and Postimfarction Cases.- Newest Information on Unstable Angina Pectoris.- Effect of Nifedipine on Relaxation and Early Left Ventricular Filling During Postpacing Ischemic Period.- Atherosclerosis.- Effect of Nifedipine on Atherosclerosis in Cholesterol-Fed Rabbits and Watanabe Heritable Hyperlipidemic Rabbits.- Natural History of Coronary Artery Disease: The Effects of Ca2+ Channel Blockade and Antiplatelet Agent on Progression or Regression of Coronary Atherosclerosis.- Effect of Nifedipine on DNA Synthesis and Cytosolic Free Calcium Concentration Stimulated by Growth Factors: A Study Using Cultured Rat Aortic Smooth-Muscle Cells.- Hypertension.- Studies on the Mechanism of the Antihypertensive Effect of Long-Term Administered Nifedipine in Patients with Benign Essential Hypertension.- Nifedipine Retard as Monotherapy for Essential Hypertension: A Randomized Controlled Cross-over Study.- Long-Term Treatment of Hypertensive Patients with Nifedipine Tablet.- Hemodynamic and Neurohumoral Effects of Nifedipine Slow-Release Tablet in the Treatment of Hypertension.- Special Topics.- Effect of Nifedipine on Serum Lipoprotein Metabolism in Patients with Essential Hypertension.- Effects of Nifedipine on Cardiovascular System, with Special Reference to Coronary Circulation.

Erscheint lt. Verlag	14.12.1989
Zusatzinfo	XIV, 138 p. 1 illus.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	246 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie ► PTA / PKA
Schlagworte	Adalat • Bluthochdruck • Bluthochdruck / Hypertonie • Calcium-Antagonisten • Cardiovascular • Herzinsuffizienz • Hypertension • Hypertonie • Nifedipin • Pharmakologie
ISBN-10	3-540-51388-4 / 3540513884
ISBN-13	978-3-540-51388-9 / 9783540513889
Zustand	Neuware