Hepatitis C

Dr. John Gallin was appointed to the dual roles of National Institutes of Health (NIH) Associate Director for Clinical Research and inaugural Chief Scientific Officer, the Clinical Center in August 2016. He served as the Director NIH Clinical Center from 1994-2017 after serving 9 years as Scientific Director of the National Institute of Allergy and Infectious Diseases (NIAID) and 12 years as Chief of the Laboratory of Host Defenses. During his tenure as Director of the NIH Clinical Center, Dr. Gallin helped to lead the design, construction, and activation of the Mark O. Hatfield Clinical Research Center, the largest hospital in the world totally dedicated to clinical research. He also oversaw the establishment of a new curriculum for clinical research training, now offered globally reaching over 25,000 students annually in 168 countries, and the development of new information systems for biomedical, translational and clinical research. In 2011, Dr. Gallin accepted, on behalf of the NIH Clinical Center, the Lasker–Bloomberg Public Service Award for its rich history of medical discovery through clinical research. His primary research interests are rare immune disorders of phagocytes, with a focus on chronic granulomatous disease (CGD). His laboratory described the genetic basis for several forms of CGD and other disorders of phagocytes and has done pioneering research that has reduced life-threatening bacterial and fungal infections in patients with these disorders. He has published more than 380 articles in scientific journals and edited two textbooks – Inflammation, Basic Principles and Clinical Correlates (Lippincott, Williams, and Wilkins, 1999, 3rd edition) and Principles and Practice of Clinical Research (Academic Press, 4th edition 2018). He has received numerous awards and honors for his accomplishments and in 2022 received the Weill Cornell Medical College Alumni Award of Distinction, the medical college’s most prestigious alumni award. Dr. Gallin is a member of the American Society for Clinical Investigation, the Association of American Physicians, the National Academy of Medicine of the National Academy of Sciences, a Master of the American College of Physicians, and a Fellow of the Royal College of Physicians-London. He retired from his administrative positions in 2023 and is now an Adjunct Senior Investigator at NIH in the Laboratory of Clinical Immunology and Microbiology in the National Institute of Allergy and Infectious Diseases. T. Jake Liang, M.D., is the Chief of the Liver Disease Section, Digestive Disease Branch at the National Institute of Diabetes and Digestive and Kidney Diseases at the National Institutes of Health in Bethesda, Maryland. Jay H. Hoofnagle, M.D., is the Director of the Division of Digestive Diseases and Nutrition in the National Institute of Diabetes and Digestive and Kidney Diseases at the National Institutes of Health in Bethesda, Maryland.

Molecular Biology of Hepatitis C Virus, M. Thomson and T.J. Liang.
Hepatitis C: Viral Markers and Quasispecies, J.-M. Pawlotsky.
Hepatitis C Virus Genotypes, P. Simmonds.
Acute Hepatitis C, J.H. Hoofnagle.
Natural History of Hepatitis C, L.B. Seeff.
Pathology of Hepatitis C, D.E. Kleiner.
Humoral Response to Hepatitis C Virus, A.J. Weiner, D. Chien, Q.-L. Choo, S. Coates, G. Kuo, and M. Houghton.
Immunopathogenesis of Hepatitis C, B. Rehermann.
Epidemiology of Hepatitis C, M.J. Alter, Y.J.F. Hutin, and G.L. Armstrong.
Worldwide Prevalence and Prevention of Hepatitis C, D. Lavanchy and B. McMahon.
Therapy of Chronic Hepatitis C, J.G. McHutchinson and J.H. Hoofnagle.
Hepatitis C and Cirrhosis, G. Fattovich and S.W. Schalm.
Hepatitis C and Hepatocellular Carcinoma, A.M. Di Bisceglie.
Hepatitis C and Liver Transplantation, M. Berenguer and T.L. Wright.
Mixed Cryoglobulinemia and Other Extrahepatic Manifestations of Hepatitis C Virus Infection, V. Agnello.
Hepatitis C Virus and Human Immunodeficiency Virus Coinfection, M. Ghany and D.T.-Y Lau.
Hepatitis C and Renal Disease, S. Zacks and M.W. Fried.
Chronic Hepatitis C and Porphyria Cutanea Tarda, J.R. Bloomer.
Hepatitis C Virus Infection and Alcohol, J. Everhart and D. Herion.
Hepatitis C in Children, M.M. Jonas.
Hepatitis C and Pregnancy, A.E. Semprini and A.R. Zanetti.
Hepatitis C and Iron, J.K. Olynyk and B.R. Bacon.
Complementary and Alternative Medicine in Hepatitis C, D.B. Strader and H.J. Zimmerman.
Development of Novel Therapies for Hepatitis C, J.Y.N. Lau and D.N. Standring.
Hepatitis C Vaccines, S. Gagneten and S.M. Feinstone.
Index.