Electrogenic Cl-Transporters in Biological Membranes

This monograph reviews electrogenic Cl- transport processes and their interaction with metabolic or ionic flows in the representative plasma membranes of all living beings. The regulation of these mechanisms, either directly or through secondary messengers, is also discussed.

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Treated here are electrogenic Cl- transport processes and their interaction with metabolic or ionic flows in representative plasma membranes of all living beings. Leading experts cover the following topics in short reviews: photon and ATP-driven Cl- transporters, proton-driven Cl- symporters, sulphate-driven Cl- antiporters, and Cl- channels in unicellular and multicellular organisms ranging from bacteria and protozoa to higher mammals. Regulation of these mechanisms either directly or through secondary messengers or via nuclear commands is also discussed. The book also elucidates the wide spectrum of new methods (e.g. patch clamping, reconstitution, molecular biology, etc.) now available for the application to various cellular plasma membrane systems, and demonstrates that certain cellular systems from simple organisms may serve as paradigms for other cellular membrane processes from more complex organisms.