Focal Therapy in Prostate Cancer (eBook)

Edited by Hashim U. Ahmed, Division of Surgery and Interventional Science, University College London, London, UK Manit Arya, Department of Urology, University College London, London, UK Peter R. Carroll, Department of Urology, University of California, San Francisco, CA, USA Mark Emberton, Division of Surgery and Interventional Science, University College London, London, UK

Contributor List, vii

Preface, xi

Section I Is there a role for Focal Therapy in Localised
Prostate Cancer?, 1

1 The Rationale for Focal Therapy of Prostate Cancer, 3

Cole Davis, Matthew Cooperberg, and Peter R. Carroll

2 Factors That Affect Patients' Choice of Treatment, 11

Deb Feldman-Stewart and Michael D. Brundage

3 Histological Trends and the Index Lesion in Localized Prostate
Cancer, 17

Vladimir Mouraviev, Thomas Wheeler, and Thomas J.
Polascik

4 Selection Criteria for Prostate Cancer Focal Therapy, 29

Rajat K. Jain, Timothy K. Ito, and Samir S. Taneja

Section II How can we accurately locate cancer within the
gland?, 37

5 Localisation of Cancer within the Gland: Biopsy Strategies,
39

Winston E Barzell and Rodrigo Pinochet

6 Localisation of Cancer within the Gland: Ultrasound Imaging,
47

Ulrich Scheipers

7 Localization of Cancer within the Prostate: Dynamic
Contrast-Enhanced MRI, 55

Philippe Puech, Anwar Padhani, Laurent Lemaitre, Nacim Betrouni,
Pierre Colin, and Arnauld Villers

8 Localization of Cancer within the Gland: Diffusion-Weighted
Magnetic Resonance Imaging of the Prostate, 66

Sophie F Riches, Nina Tunariu, and Nandita M deSouza

9 The future of Molecular and Biomolecular Imaging in Prostate
Cancer, 75

Michael S. Gee and Mukesh G. Harisinghani

Section III How can we create discrete tissue necrosis?,
85

10 Energies for Focal Ablation: Cryoablation, 87

John F. Ward

11 Focal Salvage Cryoablation in Recurrent Prostate Cancer,
98

Katsuto Shinohara

12 High-Intensity Focused Ultrasound, 106

Hashim Uddin Ahmed and Mark Emberton

13 Energies for Focal Ablation: Photodynamic Therapy, 114

Caroline M. Moore, Nimalan Arumainayagam and Mark
Emberton

14 Focal Therapy for Prostate Cancer Using Radiation, 126

Irving Kaplan, Elizabeth Genega and Neil Rofsky

15 Image Registration and Fusion for Image-Guided Focal
Ablation, 132

Dean Barratt and David Hawkes

Section IV How can we determine the success of Focal Therapy?
, 143

16 Determining Success of Focal Therapy: Biochemical and Biopsy
Strategies, 145

Al Barqawi, Paul Maroni, and David Crawford

17 Determining Success of Focal Therapy: Imaging, 153

Alex Kirkham and Clare Allen

18 Evaluating Focal Therapy: Future Perspectives, 170

Hashim Uddin Ahmed and Mark Emberton

Index, 179

Colour plate section can be found facing page 116

"Whilst the book is not designed to represent a daily
reference guide for the majority of the urological fraternity, it
clearly does what it sets out to do; provide an up-to-date and
comprehensive analysis of a treatment option that perhaps one day
we will routinely consider alongside active surveillance and
robotic surgery." (Urology News, 1 November 2012)