Neuroimmunology in Clinical Practice (eBook)

Dr Bernadette Kalman, Director of Research and Associate Professor of Neurology, Syracuse VAMC, SUNY Upstate Medical University, and Dr Thomas H. Brannagan III, Associate Professor, Weill Medical College of Cornell University, have assembled a team of leading neuroimmunology researchers and practitioners worldwide.

Neuroimmunology in Clinical Practice 1
Contents 7
Preface 9
Foreword 10
Contributing authors 11
Part I Basic science introduction to clinical neuroimmunology 15
1 The basics of cellular and molecular immunology 17
2 Major components of myelin in the mammalian central and peripheral nervous systems 25
Part II Inflammatory demyelination in the central nervous system 41
3 Multiple sclerosis 43
3.1 Epidemiology and genetics (Bernadette Kalman) 43
3.2 Immunopathogenesis (Thomas P. Leist) 49
3.3 Courses and diagnosis of MS (Bernadette Kalman) 52
3.4 Clinical features (Bernadette Kalman) 56
3.5 The pathology of MS: A quest for clinical correlation (William F. Hickey) 64
3.6 Cerebrospinal fluid (Mark S. Freedman) 68
3.7 Magnetic resonance imaging characteristics of MS (Jennifer L. Cox and Robert Zivadinov) 70
3.8 Treatment of MS (Sean Pittock) 77
4 Devic's disease 97
5 Acute disseminated encephalomyelitis and related conditions 102
Part III Autoimmune diseases of the peripheral nervous system and the muscle 129
6 Guillain-Barre syndrome 131
7 Immune-mediated chronic demyelinating polyneuropathies 137
8 Immune-mediated autonomic neuropathies 153
9 Autoimmune myasthenic syndromes: Myasthenia gravis and Lambert-Eaton myasthenic syndrome 167
10 Polymyositis and dermatomyositis 183
Part IV Disorders of the central and peripheral nervous systems related to known or assumed system-immune abnormalities 193
11 Neuro-Sjogren's syndrome 195
12 Neuro-Behcet's syndrome 199
13 Steroid-responsive encephalopathy associated with Hashimoto's thyroiditis 203
14 Rasmussen's encephalitis 205
15 Susac's syndrome 211
16 Cogan's syndrome 214
17 Neurosarcoidosis 217
18 Anti-VGKC syndromes: Isaacs' syndrome, Morvan's syndrome, and autoimmune limbic encephalitis 221
19 Paraneoplastic neurological autoimmunity 224
20 Vasculitis and connective tissue diseases 232
21 Poststreptococcal movement disorders 254
22 Neurological manifestations of gluten sensitivity 265
23 Anti-GAD associated neurological diseases 270
Index 273

"This unique book is essential reading in clinical
neuroimmunology. Written by field experts this book provides a
comprehensive description of immune mediated neurological disorders
complemented with the most pertinent and up to date scientific
data." (Immortality Medicine, 27 December
2012)