The Thalassaemia Syndromes (eBook)

Sir David John Weatherall, GBE, FRS is a British physician and researcher in molecular genetics, haematology, pathology and clinical medicine. J. B. Clegg is the author of The Thalassaemia Syndromes, 4th Edition, published by Wiley.

Authors and Contributors.

Preface to the Fourth Edition.

Preface to the First Edition.

Acknowledgements.

Part 1 Historical Background.

1. Historical Perspectives: The Many and Diverse Routes to our
Current Understanding of the Thalassaemia Syndromes.

Part 2 The Biology of The Thalassaemias.

2. Human Haemoglobin.

3. Thalassaemia: Classification and Relationship to Other
Inherited Diseases of Haemoglobin.

4. The Molecular Pathology of the Thalassaemias.

5. Pathophysiology of the Thalassaemias.

6. The World Distribution and Population Genetics of
Thalassaemia.

Part 3 Clinical Features of the Thalassaemias .

7. The beta Thalassaemias.

8. The delta beta and Related Thalassaemias.

9. The beta and delta beta Thalassaemia in Association with
Structural Haemoglobin Variants.

10. Hereditary Persistence of Fetal Haemoglobin.

11. The alpha Thalassaemias and Their Interactions with
Structural Haemoglobin Variants.

12. Thalassaemia withmental retardation or Myelodysplasia.

13. Thalassaemia Intermedia.

Part 4 Diagnosis and management of thalassaemia. .

14. Avoidance and Population Control.

15. Management and prognosis.

16. Laboratory Diagnosis of the Thalassaemias.

Part 5 The Future.

References.

Appendix.

Index.

"The book should be part of the library of every haematologist..."

JAMA on the Third Edition

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South African Medical Journal on the Third
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Clinical and Laboratory Haematology on the Third
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