Pharmacogenomics in Clinical Therapeutics (eBook)

Amitava Dasgupta, Ph.D, DABCC, FACB, Professor of Pathology and Laboratory Medicine, University of Texas Health Sciences Center at Houston, Houston, TX. Loralie J. Langman, Ph.D, DABCC, FACB, Associate Professor of Laboratory Medicine, Mayo Clinic, Rochester, MN.

List of Contributors, vii

Preface, ix

1 Pharmacogenomics Principles: Introduction to Personalized
Medicine, 1

Parvaz Madadi, PhD and Gideon Koren, MD

2 Traditional Therapeutic Drug Monitoring and Pharmacogenomics:
Are They Complementary? 15

Christine L.H. Snozek, PhD, Loralie J. Langman, PhD, and Amitava
Dasgupta, Ph.D

3 Pharmacogenomics Aspect of Warfarin Therapy, 26

Matthew D. Krasowski, MD, PhD

4 Pharmacogenetics and Cancer Chemotherapy, 39

Christine L.H. Snozek

5 Pharmacogenomic Considerations in Anesthesia and Pain
Management, 53

Christine M. Formea, PharmD and Wayne T. Nicholson, MD,
PharmD

6 Pharmacogenomics of Immunosuppressants, 70

Nicolas Picard, PharmD, PhD and Pierre Marquet, MD, PhD

7 Pharmacogenomics of Cardiovascular Drugs, 98

Linnea M. Baudhuin, PhD

8 Pharmacogenomic Aspects of Antiretroviral Therapy, 127

Natella Y. Rakhmanina, MD, PhD and John N. van den Anker, MD,
PhD

9 Pharmacogenetics of Psychoactive Drugs, 144

Jorge L. Sepulveda, MD, PhD

10 Pharmacogenomic Aspects of Adverse Drug-Drug
Interactions, 176

Loralie J. Langman, PhD and Christine L.H. Snozek, PhD

11 Microarray Technology and Other Methods in Pharmacogenomics
Testing, 185

Jorge L. Sepulveda, MD, PhD

12 Pharmacogenetic Testing in the Clinical Laboratory
Environment, 201

Mark P. Borgman, PhD and Mark W. Linder, PhD

Index, 225

"This book is unique in its focus on the application of
pharmacogenomics in clinical therapeutics."
(Doody's,

19 January 2013)