Dioxins and Health (eBook)

ARNOLD SCHECTER, MD, MPH, is Professor of Environmental and Occupational Health Sciences at the University of Texas School of Public Health. He is a preventive medicine physician-researcher who has studied the effects of dioxin and related chemical exposure around the world. Most recently, his research has focused on emerging POPs and endocrine disruptors in human milk, blood, and food. Dr. Schecter has served on EPA dioxin advisory panels and ATSDR/CDC dioxin, PCB, and PCDF review groups. Moreover, he has worked with the NIEHS, NIH, and NTP to communicate dioxin carcinogenicity assessments.

PREFACE xi

ACKNOWLEDGMENT xvi

ABOUT THE EDITOR xvii

CONTRIBUTORS xix

LIST OF TABLES AND FIGURES xxiii

1 PERSISTENT ORGANIC POLLUTANTS: AN OVERVIEW 1

Daniele Wikoff, Lauren Fitzgerald, and Linda
Birnbaum

2 TOXICITY EQUIVALENCE FACTORS FOR DIOXIN AND RELATED COMPOUNDS
37

Michael DeVito

3 HISTORIC AND NEWER PERSISTENT ORGANIC POLLUTANTS IN FOOD
53

Janice Huwe

4 FLAME RETARDANTS: POLYBROMINATED DIPHENYL ETHERS AND THEIR
REPLACEMENTS 89

Thomas F. Webster and Heather M. Stapleton

5 PHARMACOKINETICS OF 2,3,7,8-TETRACHLORODIBENZO-AND RELATED
COMPOUNDS P-DIOXIN 109

James R. Olson

6 IMMUNOMODULATION BY PERSISTENT ORGANIC POLLUTANTS
171

Robert W. Luebke, Jamie C. DeWitt, Dori R. Germolec, Keith D.
Salazar, and Nancy I. Kerkvliet

7 DEVELOPMENTAL NEUROTOXICITY OF DIOXINS 193

G. Jean Harry and Pamela J. Lein

8 EPIDEMIOLOGICAL EVIDENCE ON THE HEALTH EFFECTS OF
PERFLUOROOCTANOIC ACID 229

Kyle Steenland, Tony Fletcher, and David A. Savitz

9 POLYBROMINATED P-DIOXINS AND DIBENZO-DIBENZOFURANS
255

Kurunthachalam Kannan, Chunyang Liao, and Hyo-Bang Moon

10 EPIDEMIOLOGICAL STUDIES ON CANCER AND EXPOSURE TO DIOXINS AND
RELATED COMPOUNDS 303

Lennart Hardell and Mikael Eriksson

11 REPRODUCTIVE AND DEVELOPMENTAL EPIDEMIOLOGY OF DIOXINS
359

Anne Sweeney, Deborah J. del Junco, Marcella Warner, and Brenda
Eskenazi

12 BISPHENOL A 381

Thaddeus T. Schug, Sarah A. Vogel, Laura N. Vandenberg, Joe M.
Braun, Russ Hauser, Julia A. Taylor, Frederick S. vom Saal, and
Jerold J. Heindel

13 PHTHALATES: HUMAN EXPOSURE AND RELATED HEALTH EFFECTS
415

John D. Meeker and Kelly K. Ferguson

14 THE SEVESO ACCIDENT 445

Angela Cecilia Pesatori and Pier Alberto Bertazzi

15 AGENT ORANGE: HEALTH AND ENVIRONMENTAL ISSUES IN VIETNAM,
CAMBODIA, AND LAOS 469

Susan Hammond and Arnold Schecter

16 THE YUSHO AND YUCHENG RICE OIL POISONING INCIDENTS
521

Yoshito Masuda and Arnold Schecter

17 THE BINGHAMTON, NEW YORK, ELECTRICAL TRANSFORMER FIRE
INCIDENT OF 1981 553

Nancy Kim and Arnold Schecter

18 THE YUSHCHENKO DIOXIN POISONING: CHRONOLOGY AND
PHARMACOKINETICS 567

John Jake Ryan

19 POPs AND HUMAN HEALTH RISK ASSESSMENT 579

David T. Szabo and Anne E. Loccisano

INDEX 619

"This book is certain worthy of a place on your bookshelf
if you are interested in environmental contamination or POPs in
general." (International Journal of Toxicology, 1
January 2013)

"I would also consider it suitable as an advanced text for
learning form as it indicates the range of information that has to
be examined when making toxicological judgements which affect
political decisions, including judgements that have to be taken in
the face of pressure from lobbyists." (British
Toxicology Society New, 1 November 2012)