Imaging and Focal Therapy of Early Prostate Cancer (eBook)

Thomas J. Polascik (Herausgeber)

eBook Download: PDF
2012 | 2013
XIV, 396 Seiten
Humana Press (Verlag)
978-1-62703-182-0 (ISBN)

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Imaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy,  ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail.
 
Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer.



Thomas J. Polascik MD FACS
Department of Surgery, Duke Cancer Institute, Durham, NC, USA
Imaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy, ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer.

Thomas J. Polascik MD FACSDepartment of Surgery, Duke Cancer Institute, Durham, NC, USA

Part IScientific Foundation for the Focal Therapy ConceptChapter 1Focal Therapy in Other Genitourinary Systems: Renal Cell CarcinomaJoseph A. Graversen and Jaime LandmanChapter 2Changing Landscape of Prostate Cancer Favoring Low Risk Prostate Cancer: Implications for Active Surveillance Versus Focal TherapyByron H. Lee,  Peter R. Carroll, and  Eric A. KleinChapter 3Active Surveillance and Focal Therapy: A European Perspective Hendrick Van Poppel and Steven Joniau Chapter 4Pathologic Basis for Focal Therapy: Understanding Cancer Grade, Volume and Spatial LocationThomas J. Polascik, Arnauld Villers, Thomas M. Wheeler,   David G. Bostwick, Rodolfo Montironi,  Pierre Nevoux, and Vladimir MouravievChapter 5Identifying the Index LesionMarkos Karavitakis, Mark Emberton, and Hashim Uddin AhmedChapter 6Molecular Identification of the Indolent Versus Lethal TumorG.H.J.M. Leyten and J.A. SchalkenPart IIAdvances in Prostate Biopsy TechniqueChapter 7Biopsy Strategies to Detect Small Prostate CancersRyan Berglund and J. Stephen Jones Chapter 83-D Image-guided Mapping Biopsy for Defining Spatial Distribution of Prostate CancerSamuel Clark Berngard, Kyle O. Rove, Jens Rassweiler, Oliver Kalthoff, Marcel Hruza, andE. David Crawford Chapter 9Stereotactic, Image-guided Robotic BiopsyOsamu Ukimura and André Luis de Castro AbreuChapter 10Multimodality MRI-guided Targeting Arnauld Villers and Adil Ouzzane Chapter 11 Quality Assurance in Prostate Biopsy Sampling, Processing, and Reporting: A New Pathologic Paradigm for Prostate Cancer DiagnosisDavid G. Bostwick Part IIIFunctional and Molecular ImagingChapter 12Contrast-enhanced UltrasonographyM. Smeenge, M. Mischi, M.P. Laguna, J.J.M.C.H. de la Rosette and H. WijkstraChapter 13Prostate ElastrographyStephen Rosenzweig, Liang Zhai, and Kathryn R. NightingaleChapter 14Multi-parametric Magnetic Resonance Imaging Approaches in Focal Prostate Cancer TherapySadhna Verma, Michael A.S. Lamba, Daniel B. Vigneron, Adam Jung, and John KurhanewiczChapter 15Nanomedicines for Diagnosis and Treatment of Prostate CancerNazila Kamaly, Archana Swami, Ryan Wagner, and Omid Cameron FarokhzadChapter 16New Horizons in Molecular Imaging of Prostate CancerBaris Turkbey and Peter L. Choyke Part IVFocal Therapy Nomenclature and Patient SelectionChapter 17Prostate Focal Therapy: Definitions and Common TerminologyJohn F. WardChapter 18Selection Criteria for Focal Therapy of Prostate CancerVladimir Mouraviev and Thomas J. Polascik Chapter 19Standardization of Focal Therapy ProtocolsLouise Dickinson, Hashim Uddin Ahmed, and Mark EmbertonPart VNovel Thermoablation Technologies for Focal TherapyChapter 20High Intensity Focused UltrasoundSatoru Muto and Shigeo HorieChapter 21Photodynamic Therapy for Early Prostate CancerCaroline M. Moore and Mark Emberton Chapter 22MRI-guided Laser Ablation for Localized Prostate Cancer Uri Lindner and John Trachtenberg Chapter 23Cell Electroporation Mechanisms and Pre-clinical Foundation for Focal TherapyMark V. Ortiz and Rafael V. DavalosChapter 24HistotripsyWilliam W. RobertsChapter 25CryoablationDavid A. Levy and J. Stephen JonesChapter 26Optimizing Ablative Therapy: Manipulating the MicroenvironmentJohn M. Baust, Kimberly Santucci, Anthony Robilotto, Andrew A. Gage  and John G. BaustPart VIPost-treatment Follow-up and Future DirectionsChapter 27Setting Rules for Postablation and Follow-up David S. Finley and Arie S. Belldegrun Chapter 28Roadmap for Focal TherapyThomas J. Polascik and Vladimir Mouraviev

Erscheint lt. Verlag 2.12.2012
Reihe/Serie Current Clinical Urology
Zusatzinfo XIV, 396 p. 101 illus., 82 illus. in color.
Verlagsort Totowa
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Medizinische Fachgebiete Radiologie / Bildgebende Verfahren
Medizin / Pharmazie Medizinische Fachgebiete Urologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Schlagworte Constrast enhanced ultrasonography • Elastography • Spatial focality • Stereotactic image guided biopsy • Thermoblation
ISBN-10 1-62703-182-0 / 1627031820
ISBN-13 978-1-62703-182-0 / 9781627031820
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