Molecular Techniques for the Study of Hospital Acquired Infection (eBook)

Shabbir Simjee, Ph.D. is a Senior Microbiologist at Eli Lilly & Company, where he specializes in antimicrobial susceptibility testing and the interpretation of antimicrobial susceptibility data according to NCCLS and BSAC standards. He has served as Editor of The Journal of Antimicrobial Chemotherapy and currently serves as an Editorial Board Member for Antimicrobial Agents and Chemotherapy as well as Section Editor (Molecular Microbiology) for the International Journal of Antimicrobial Agents. Dr. Simjee has served on a number of FDA advisory committees. Steven Foley, Ph.D. is an Associate Research Scientist for the National Farm Medicine Center, Marshfield Clinic Research Foundation, as well as Clinical Professor of Clinical Microbiology at the University of Wisconsin. His research interests include understanding the mechanisms that Escherichia coli employ to resist being killed by vertebrate immune system constituents and the development and utilization of genotypic and phenotypic methods to track enteric bacterial pathogens and their virulence and antimicrobial resistance factors through the food animal production environment. Anne Chen, M.D. is a Senior Staff Physician, Division of Infectious Diseases at the Henry Ford Hospital, Detroit, Michigan as well as Assistant Professor of Medicine at Wayne State University School of Medicine. She is Board Certified in Internal Medicine and Infectious Disease and is currently researching Candida epidemiology in the burn unit. Marcus J. Zervos, M.D. is the Medical Director of Infection Control and Division Head of Infectious Disease, Department of Internal Medicine at Henry Ford Hospital as well as Clinical Professor of Medicine in the Department of Internal Medicine, Infectious Diseases Section at Wayne State University School of Medicine. He chairs the Infection Control Committee at the Henry Ford Hospital and is certified by the American Board of Internal Medicine and Infectious Diseases. Dr. Zervos serves on the boards of several journals in infectious disease, microbiology and internal medicine, including Infectious Diseases in Clinical Practice and his role as Section Editor for the journal Infection Control and Hospital Epidemiology.

Contributors.

Forword.

Preface.

Dedication.

I. Introduction to Healthcare Associated Infections and Their
Control.

1. The Hospital and Ambulatory Care Environment (Anne Y. Chen
and Hiren Pokharma).

2. Pathogen Transmission in the Healthcare Setting (Sonja
Hansen and Ralf-Peter Vonberg).

3. Infection Control Basics (Louise-Marie Dembry and Carlos
Torres-Viera).

4. Cost-Effectiveness of IC Program (Marc-Oliver Wright and
Eli N. Perencevich).

5. Outbreak Investigations (Importance of the Healthcare
Epidemiologist) (Marcus J. Zervos).

6. Pathogen Elimination: Antibiotic and Disinfectant Use and the
Development of Resistance (Steven L. Foley, Beilei Ge, Carl M.
Schroeder, and Arron M. Lynne).

II. Techniques to Characterize Nosocomial Pathogens.

7. Rapid PCR Screening Methods (Ngolela Esther Babady,
Frankling Cockerill and Robin Patel).

8. Restriction Analysis Techniques (Richard V. Goering, Mary
Stemper, SanjayShukla and Steven Foley).

9. Pulsed-field Gel Electrophoresis (Mary Stemper, Steven
Foley Richard V. Goering, and Sanjay Shukla).

III. Application of Techniques to Characterize Predominant
Nosocomial Pathogens.

10. Staphylococcus aureus (Vanthida Huang).

11. Escherichia coli (Johann D. D. Pitout).

12. Fungal Infections (Jose A. Vazquez).

Index.