The Evidence Base of Clinical Diagnosis (eBook)

Andre Knottnerus, Professor of General Practice, Maastricht University. He is involved in the Cochrane movement for drawing up tools for accurate diagnostic testing Frank Buntinx, Professor, Department of Public Health, Leuven University. He is one time chair of the Cochrane Collaboration Diagnostic and Screening Tests Working Group

List of Contributors, vii

Preface, xi

1 General introduction: evaluation of diagnostic procedures,
1

J. Andre Knottnerus, Frank Buntinx, and Chris van Weel

2 The architecture of diagnostic research, 20

R. Brian Haynes and John J. You

3 Assessment of the accuracy of diagnostic tests: the
cross-sectional study, 42

J. Andre Knottnerus and Jean W. Muris

4 Diagnostic testing and prognosis: the randomized controlled
trial in test evaluation research, 63

Jeroen G. Lijmer and Patrick M. M. Bossuyt

5 The diagnostic before-after study to assess clinical
impact, 83

J. Andre Knottnerus, Geert-Jan Dinant, and Onno P. Van
Schayck

6 Designing studies to ensure that estimates of test accuracy
will travel, 96

Les M. Irwig, Patrick M. M. Bossuyt, Paul P. Glasziou,
Constantine Gatsonis, and Jeroen G. Lijmer

7 Analysis of data on the accuracy of diagnostic tests,
118

J. Dik F. Habbema, Rene Eijkemans, Pieta Krijnen, and J. Andre
Knottnerus

8 Multivariable analysis in diagnostic accuracy studies: what
are the possibilities?, 146

Frank Buntinx, Bert Aertgeerts, Marc Aerts, Rudi Bruyninckx, J.
Andre Knottnerus, Ann van den Bruel, and Jef van den Ende

9 Standards for reporting on diagnostic accuracy studies,
167

Patrick M. M. Bossuyt and Nynke Smidt

10 Guidelines for conducting systematic reviews of studies
evaluating the accuracy of diagnostic tests, 180

Frank Buntinx, Bert Aertgeerts, and Petra Macaskill

11 Producing and using clinical prediction rules, 213

Tom Fahey and Johan van der Lei

12 Clinical problem solving and diagnostic decision making: a
selective review of the cognitive research literature, 237

Alan Schwartz and Arthur S. Elstein

13 Improving test ordering and its diagnostic cost-effectiveness
in clinical practice--bridging the gap between clinical
research and routine health care, 256

Ron Winkens, Trudy van der Weijden, Hans Severens, and Geert-Jan
Dinant

14 Epilogue: overview of evaluation strategy and challenges,
273

J. Andre Knottnerus, Ann van den Bruel, and Frank
Buntinx

Index, 285

"An invaluable reference ophthalmologists involved in conduting or
interpreting studies on diagnostic research." (Eye News, 1 October
2010)"



This is a thorough compilation of clinical research methods and
practices." (Doody's Reviews, March 2009)