Management Strategies in Antithrombotic Therapy (eBook)
366 Seiten
John Wiley & Sons (Verlag)
978-0-470-51814-4 (ISBN)
significant problems in cardiovascular medicine. It underlies the
clinical presentation of acute coronary syndromes, including
unstable angina and non-ST-segment elevation myocardial infarction
(NSTEMI) and ST-segment elevation myocardial infarction.
More and more individuals are stricken with an acute MI and
undergo a percutaneous coronary intervention (PCI). Several reasons
apply, including an increasingly aged population, the growing
burden of chronic risk factors such as diabetes, obesity, sedentary
behaviour, and improvements in early recognition and intervention.
Thrombus formation also results in substantial morbidity and
mortality. Despite significant advances in prevention and treatment
of venous thromboembolism, pulmonary embolism remains a common
preventable cause of hospital deaths. Implementing the most
appropriate, and safe, anticoagulation therapy across the spectrum
of cardiovascular disease in the presence of a wide range of other
risk factors remains a challenge.
Written by leading authorities in the field, Management
Strategies in Antithrombotic Therapy offers a comprehensive
review of antithrombotic therapy, including the latest therapies,
risk factors and evidence-based strategy. The book acquaints
readers with the data behind the commonly used antithrombotic
agents and assists them in formulating a sound, evidence-based
therapeutic strategy appropriate for each patient.
This book is an invaluable resource for all postgraduate
students and specialist physicians in cardiovascular medicine,
cardiac and vascular surgery, and critical care.
Arman T. Askari, MD. Associate Director, Cardiovascular Medicine Training Program, The Cleveland Clinic, Ohio, USA Dr Michael A. Lincoff, MD. Department of Cardiovascular Medicine, Cleveland Clinic Heart Center, The Cleveland Clinic, Ohio, USA
Abbreviations and Acronyms.
Preface.
Chapter 1. Thrombosis and Antithrombotics in Vascular
Disease.
1.1 The Burden of Thrombosis.
1.2 Essential components of thrombosis.
1.3 Thrombosis in the acute ischemic syndromes.
1.4 Venous thromboembolic disease.
1.5 The ideal antithrombotic agent.
Chapter 2. Aspirin.
2.1 Introduction.
2.2 Pharmacology.
2.3 Clinical uses of aspirin.
2.4 Conclusions.
Chapter 3. Thienopyridines - Ticlopidine and
Clopidogrel.
3.1 Introduction.
3.2 Pharmacology.
3.3 Clinical uses of the thienopyridines.
3.4 Conclusions.
Chapter 4. Platelet Glycoprotein IIb/IIIa Inhibitors.
4.1 Introduction.
4.2 GP IIb/IIIa receptor inhibitors.
4.3 GP IIb/IIIa inhibitors during percutaneous coronary
revascularization.
4.4 GP IIb/IIIa inhibitors in the management of non-st-elevation
ACS.
4.5 GP IIb/IIIa inhibitors in the management of acute STEMI.
4.6 Safety of GP IIb/IIIa inhibitors.
4.7 Summary.
Chapter 5. Unfractionated Heparin.
5.1 Introduction.
5.2 Pharmacology.
5.3 Clinical uses of UH.
5.4 Clinical considerations.
5.5 Conclusions.
Chapter 6. Low-Molecular-Weight Heparins.
6.1 Introduction.
6.2 Comparisons between UH and LMWH.
6.3 Clinical uses of LMWH.
6.4 Conclusions.
Chapter 7 Direct Thrombin Inhibitors.
7.1 Introduction.
7.2 Overview of DTIs.
7.3 Clinical uses of DTIs.
7.4 Summary.
Chapter 8. Fibrinolytic agents.
8.1 Introduction.
8.2 Fibrinolytic agents for STEMI.
8.3 Fibrinolytics for VTE.
8.4 Conclusions.
Chapter 9. Acute ST-Segment-Elevation Myocardial
Infarction.
9.1 Introduction.
9.2 Definitive therapy.
9.3 Adjunctive therapy.
9.4 Recommendations.
9.5 Conclusions.
Chapter 10. Acute Coronary Syndromes: Unstable Angina
/Non-ST-Segment-Elevation Myocardial Infarction (NSTE ACS).
10.1 Introduction.
10.2 Antithrombotic approach to patients with ACS/NSTEMI.
10.3 Early invasive versus early conservative strategies.
10.4 Recommendations.
10.5 Conclusions.
Chapter 11 Anticoagulation Strategies for Patients Undergoing
Percutaneous Coronary Intervention.
11.1 Introduction.
11.2 Antiplatelet therapy.
11.3 Antithrombotic therapy.
11.4 Special populations.
11.5 Recommendations.
11.6 Conclusions.
Chapter 12 Venous Thromboembolic Disease.
12.1 Introduction.
12.2 Risk of VTE.
12.3 Prevention of VTE.
12.4 Treatment of VTE.
12.5 Conclusions.
Chapter 13. Heparin-Induced Thrombocytopenia.
13.1 Introduction.
13.2 Incidence.
13.3 Pathogenesis.
13.4 Clinical manifestations.
13.5 Diagnosis.
13.6 Prevention.
13.7 Treatment.
13.8 Conclusions.
Index.
"This book is an invaluable resource for all postgraduate students and specialist physicians in cardiovascular medicine, cardiac and vascular surgery, and critical care." (Doody's, April 2008)
| Erscheint lt. Verlag | 2.8.2008 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Innere Medizin | |
| Schlagworte | Cardiovascular Disease • Kardiovaskuläre Erkrankungen • Kardiovaskuläre Erkrankungen • Medical Science • Medizin • Thrombose |
| ISBN-10 | 0-470-51814-6 / 0470518146 |
| ISBN-13 | 978-0-470-51814-4 / 9780470518144 |
| Haben Sie eine Frage zum Produkt? |
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