Basic Biostatistics for Geneticists and Epidemiologists (eBook)

Robert C. Elston Department of Epidemiology and Biostatistics, Case Western Reserve University, USA. William D. Johnson Pennington Biomedical Research Center, Louisiana State University, USA.

Preface.

1. Introduction: The role and Relevance of Statistics, Geneticsand Epidemiology In Medicine.

2. Populations, Samples, and Study Design.

3. Descriptive Statistics.

4. The Laws of Probability.

5. Random Variables and Distributions.

6. Estimates and Confidence Limits.

7. Significance Tests and Tests of Hypotheses.

8. Likelihood Ratios, Bayesian Methods and MultipleHypotheses.

9. The Many Uses of Chi-Square.

10. Correlation and Regression.

11. Analysis of Variance and Linear Models.

12. Some Specialized Techniques.

13. Guides to a Critical Evaluation of Published Reports.

Epilogue.

Review Problems.

Answers to Odd-Numbered Problems.

Appendix.

Index.

"The book is unusual in having less ambitious goals than the average statistics textbook. The focus is not to teach applications but, as the preface maintains, simply to enable readers to knowledgeably read the new literature, to understand the statistical methods used, and thereby to better keep abreast of new findings in epidemiology and genetics." (JAMA, September 13, 2010)

"This is a well-written and comprehensive review of the basic (and not-so-basic) concepts and techniques in biostatistics. It is understandable to biologists and clinicians, while still providing useful pointers and reminders to statisticians. It is worth a place on the bookshelves of all researchers in genetics, regardless of their statistical expertise." (Human Genetics, February 2010)

"Anyone who wishes to critically read biomedical literature will find the knowledge gained from reading [the text] of great value." (American Journal of Epidemiology, 2009)