Clinical Cancer Prevention

Allocating cancer directed expenditures - Tensions between prevention, early detection and treatment.- Lessons learned from prevention programs: Different endpoints should be used in secondary and tertiary prevention.- Biomarkers for early detection and as surrogate endpoints in cancer prevention trials: Issues and opportunities.- Targeting polyamines and inflammation for cancer prevention.- Thinking about the role (largely ignored) of heavy metals in cancer prevention: Hexavalent chromium and melanoma as a case in point.- Hepatitis B virus and cancer prevention.- Chemoprevention of hepatocellular carcinoma in chronic hepatitis C.- Nutritional aspects of primary prostate cancer prevention.- Prostate cancer prevention with 5 alpha reductase inhibitors.- Hormone replacement therapy and breast cancer.- Physical activity and breast cancer: Review of the epidemiologic evidence and biologic mechanisms.- Prevention of breast cancer by newer SERMs and the future.- Chemoprevention of hormone receptor-negative breast cancer: new approaches needed.