Inflammatory Diseases of Blood Vessels

Gary S. Hoffman, M.D., M.S. is Chairman of the Department of Immunologic Diseases and Director of the Center for Vasculitis Care and Research, and holds the Harold C. Schott Chair for Immunologic Diseases at the Cleveland Clinic Foundation, Ohio, and is founder and Chairman of the International Network for the Study of the Systemic Vasculitides (INSSYS). Repeatedly listed in "The Best Doctors in America", Professor Hoffman is the former Head of Vasculitis and Related Diseases at the National Institutes of Health, Bethesda, Maryland. Cornelia M. Weyand, M.D., Ph.D. is a Professor of Medicine and Immunology at the Mayo Medical School, a Consultant in the Department of Medicine at the Mayo Clinic, and the Barbara Woodward Lips Professor at the Mayo Clinic Foundation in Rochester, Minnesota. The author of numerous publications, she is a Consulting Editor for the Journal of Clinical Investigation. Professor Weyand completed additional immunology training at Stanford University, California, and is the recipient of numerous national and international awards. Carol A. Langford, MD, MHS, FACP, was a senior investigator within the Immunologic Diseases Section of the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH) from 1994 to 2004. At the NIH, Dr. Langford's research focused on vasculitic diseases, where she was Principal Investigator for nine vasculitis-related protocols. While at the NIH, Dr. Langford received an NIAID Special Act of Service Award in 2001 and was the recipient of NIAID Staff Recognition Awards from 1998 through 2004. In 2004, Dr. Langford joined the Cleveland Clinic to become Director of the Center for Vasculitis Care and Research within the Department of Immunologic Diseases. She is an Associate Professor of Medicine of the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. A frequently invited lecturer at national and international medical meetings, Dr. Langford has authored more than 50 scientific papers and chapters on vasculitis. Joerg J. Goronzy, Stanford University School of Medicine, Stanford, CA, USA.

List of Contributors Preface Section I. Biology of Blood Vessels and Mechanisms of Vascular Inflammation 1 Vascular Development Domenico Ribatti and Enrico Crivellato 2 Vascular Repair Christian Troidl, Kerstin Troidl, Georg Jung, Thomas Schmitz-Rixen and Wolfgang Schaper 3 Leukocyte Trafficking Braedon McDonald and Paul Kubes 4 Dendritic Cells and Vascular Inflammation Cornelia M. Weyand 5 T Cells and Vascular Inflammation Jorg J. Goronzy 6 Autoantibodies and Vascular Inflammation A.Rutgers, J.S.F. Sanders, J.W. Cohen Tervaert, C.G.M. Kallenberg 7 Neutrophils and Vascular Inflammation Matthew David Morgan and Caroline OS Savage 8 Cytokines and Vascular Inflammation Maria C Cid, Marc Corbera-Bellalta, Ester Planas-Rigol, Ester Lozano, Georgina Espigol-Frigole, Ana Garcia-Martinez, Jose Hernandez-Rodriguez, Marta Segarra 9 Oxidative Stress and Vascular Inflammation David G. Harrison 10 Hemostasis and Vascular Inflammation Lawrence Leung and John Morser 11 Animal Models of Vasculitis Masato Nose 12 Arteries, Smooth Muscle Cells, and Genetic Causes of Thoracic Aortic Aneurysms Amy J. Reid and Dianna M. Milewicz 13 Innate Immunity in Atherosclerosis Shuang Chen, Prediman K. Shah and Moshe Arditi 14 Adaptive Immunity in Atherosclerosis Jan Nilsson Section II. Primary Autoimmune Vascular Diseases 15 Historical Perspectives Vasculitis Eric L. Matteson 16 Approach to the Differential Diagnosis of Vasculitis Eamonn S. Molloy and Carol A. Langford 17 Imaging of medium and large vessels (CT/PET/MR) Thorsten Alexander Bley 18 Kawasaki disease Rae S.M. Yeung 19 Henoch-Schonlein Purpura Philip J. Hashkes and Alexandra Villa-Forte 20 Polyarteritis Nodosa Eli M. Miloslavsky and John H. Stone 21 Microscopic polyangiitis Coen Stegeman 22 Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Gary S. Hoffman, Carol A. Langford and Ulrich Specks 23 Churg Strauss Syndrome (Eosinophilic Granulomatosis with Polyangiitis, EGPA) Christian Pagnoux and Loic Guillevin 24 Giant cell arteritis Cornelia M. Weyand and Jorg J. Goronzy 25 Takayasu's arteritis Kathleen Maksimowicz-McKinnon and Gary S. Hoffman 26 Behcet's Syndrome Yusuf Yazici, Ismail Simsek and Hasan Yazici 27 Cogan's Syndrome Rex M. McCallum and E. William St. Clair 28 Idiopathic cryoglobulinemic vasculitides Benjamin Terrier and Patrice Cacoub 29 Primary central nervous system vasculitis Rula A. Hajj-Ali and Leonard H. Calabrese 30 Single organ vasculitis Jose Hernandez-Rodriguez and Gary S. Hoffman 31 Primary cutaneous vasculitis Jeffrey P. Callen 32 Buerger's disease (thromboangiitis obliterans) Ahmet Ruchan Akar and M. Serkan Durdu Section III. Secondary Causes of Vasculitis 33 Virus-associated vasculitides Dimitrios Vassilopoulos and Leonard H. Calabrese 34 Drug-induced vasculitis Peter A. Merkel 35 Rheumatoid vasculitis Kimberly P. Liang, Carl Turesson, Larry W. Moreland 36 Vasculopathy/Vasculitis and progressive systemic sclerosis Nezam Altorok, Omar R. Kahaly and Bashar Kahaleh 37 Vasculitis and Sjogren's syndrome George E. Fragoulis and Haralampos M. Moutsopoulos 38 Vasculitis in systemic lupus erythematosus Ricardo Garcia and Andras Perl 39 Vasculitis in the Idiopathic Inflammatory Myopathies Frederick W. Miller and Chester V. Oddis 40 Vasculitis and relapsing polychondritis Tanaz A. Kermani and Kenneth J. Warrington 41 Systemic Vasculitis in Sarcoidosis Alexandra Villa-Forte and Gary S. Hoffman 42 Vasculitis as a Paraneoplastic Syndrome and Direct Tumour Invasion of Vessels Claire E. Barber and Simon Carette Section IV. Recognizing Risks and Treating Damage from Vasculitis 43 Cholesterol and Modifications of Cholesterol in Rheumatic Disorders Jan Willem Cohen Tervaert 44 Prevention and treatment of medical complications Atul Khasnis and Carol A. Langford 45 Ophthalmic Risks and Complications Aassociated with the Treatment of Systemic Vasculitis Steven Yeh and James T. Rosenbaum 46 Subglottic Stenosis of Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Rahul Seth and Daniel S. Alam 47 Sino-Nasal Manifestations of Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Daniel S. Alam, Rahul Seth, Raj Sindwani 48 Neurologic Damage of Vasculitis C. David Lin 49 Endstage Renal Disease and Vasculitis Kirsten de Groot and Charles Pusey 50 Cardiothoracic Surgery for Takayasu's Arteritis and Giant Cell Arteritis Turki Albacker and Lars Svensson 51 Peripheral Vascular Surgery for Takayasu's Arteritis and Giant Cell Arteritis Ravi R. Rajani and Vikram S. Kashyap Index