Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition

John C Watkinson MSc(Nuclear Medicine;London).MS(London).FRCS (General Surgery).FRCS(ENT).DLO. One -Time Honorary Senior Lecturer and Consultant ENT/Head and Neck and Thyroid Surgeon. Queen Elizabeth Hospital. University of Birmingham NHS Trust and the Royal Marsden and Brompton Hospitals, Fulham Road, Chelsea, London, UK. Honorary Consultant ENT/Head and Neck and Thyroid Surgeon.Great Ormond Street Hospital (GOSH) and St Georges Hospital NHS Trust, Tooting, London. Honorary Senior Anatomy Demonstrator, University College London (UCL). Business Director, Endocrine MDT. The Bupa Cromwell Hospital. Kensington, London. Ray Clarke, Consultant Paediatric Otolaryngologist, Royal Liverpool Children's Hospital, Alder Hey, Liverpool, UK

Volume 1. Basic Science. CELL BIOLOGY. Molecular Biology . Genetics in Otology and Neurotology. Gene Therapy. Mechanisms of Anticancer Drugs. Radiotherapy. Apoptosis and Cell Death. Stem Cells. Aetiology and Pathogenesis of Goitre. Genetics of Endocrine. WOUND HEALING. Soft and Hard Tissue Repair. Skin Flap Physiology. Biomaterials, Tissue Engineering and their Application. IMMUNOLOGY. Defence Mechanisms. Allergy: Basic Mechanisms and Tests. Evaluation of the Immune System. Evaluation of the Immune System. HPV Molecular Biology. Rheumatological Diseases. MICROBIOLOGY. Microorganisms. Viruses and Antiviral Agents. Fungal Infections. Antimicrobial Therapy. HIV and Otolaryngology. HAEMATOLOGY. Blood Groups, Blood Components and Alternatives to Blood Transfusion. Haemato-Oncology. Haemostasis: Normal Physiology, Disorders of Haemostasis and Thrombosis. PHARMACOTHERAPEUTICS. Drug Therapy in Otology. Drug Therapy in Rhinology. Drug Therapy in Laryngology and Head and Neck Surgery. PERIOPERATIVE MANAGEMENT. Preparation of the Patient for Surgery. Recognition and Management of the Difficult Airway. Adult Anaesthesia. Adult Critical Care. Paediatric Intensive Care. SAFE AND EFFECTIVE PRACTICE. Training and Accreditation and Maintenance of Skills. Communication and the Medical Consultation. Clinical Governance Improving the Quality of Patient Care. Medical Ethics. Medical Jurisprudence in Otorhinolaryngology. Non-Technical Skills for Surgeons. INTERPRETATION AND MANAGEMENT OF DATA. Epidemiology. Outcomes Research. Evidence-Based Medicine. Critical Appraisal Skills. RECENT ADVANCES IN TECHNOLOGY. Electrophysiology and Monitoring. Optical Coherence Tomography. Positron Emission Tomography and Integrated PET/CT. Image Guided Surgery, 3D Planning and Reconstruction. Interventional techniques. Laser Principles in Otolaryngology, Head and Neck Surgery. Contact Endoscopy. Endocrine Surgery. OVERVIEW. History of Thyroid and Parathyroid Surgery. Developmental Anatomy of the Thyroid and Parathyroid Glands. Developmental Anatomy of the Pituitary Gland. Physiology of the Thyroid and Parathyroid Glands. Physiology of the Pituitary Gland. Imaging in Head and Neck Endocrine Disease. Thyroid Cytology and Histopathology of Head and Neck Endocrine Disease. THYROID DISEASE. Clinical Evaluation of the Thyroid Patient. Investigation of Thyroid Disease. Benign Thyroid Disease. Management of Differentiated Thyroid Cancer. Management of Medullary Thyroid Cancer. Management of Anaplastic Thyroid Cancer/Lymphoma. Management of Recurrent and Metastatic Disease. Adjuvant Treatments in Thyroid Cancer. THYROID SURGERY. Thyroidectomy. Surgery for Locally Advanced and Nodal Disease. Minimally Invasive and Robotic Thyroid Surgery. Management of the Enlarged Thyroid. PARATHYROID DISEASE. Clinical Evaluation of Hypercalcaemia. Investigation of Hyperparathyroidism. Management of Hyperparathyroidism. Management of Persistent and Recurrent Hyperparathyroidism. Management of Parathyroid Cancer. Bilateral Neck Exploration. PARATHYROID SURGERY. Minimally Invasive Parathyroidectomy. Surgical Failure and Reoperative Surgery. THYROID AND PARATHYROID OUTCOMES. Complications of Thyroid/Parathyroid Surgery and how to avoid them. Thyroid and Parathyroid Surgery: Audit and Outcomes. Medicolegal Aspects of Head and Neck Endocrine Surgery. PITUITARY DISEASE. Clinical Evaluation of the Pituitary Patient. Investigation of Pituitary Disease. Primary Pituitary Disease. Recurrent Pituitary Disease. Adjuvant Treatment of Pituitary Disease. Rhinology. Anatomy of Nose, Paranasal Sinuses and Skull Base. Outpatient Assessment. Physiology of the Nose and Paranasal Sinuses. Measurement of the Nasal Airway. Allergic Rhinitis. Non Allergic Rhinitis. Occupational Rhinitis. Rhinosinusitis. Nasal Polyposis. Fungal Rhinosinusitis. Medical Management of Rhinosinusitis. Surgical Management of Rhinosinusitis. The Frontal Sinus. Mucocoeles. Complications of Rhinosinusitis. Relationship of Upper and Lower Respiratory Tract. Nasal Septum and Nasal Valve. Nasal Septal Perforation. The Management of the Enlarged Turbinate. Epistaxis. Nasal and Facial Fractures. CSF Rhinorrhoea. Granulomatous Conditions of the Nose. Olfaction. Disorders of the Orbit. Diagnosis and Management of Facial Pain. Juvenile Angiofibroma. Endoscopic Management of Sinonasal Tumours. Management of Pituitary and Parasellar Diseases. Extended Anterior Skull Base Approaches. Radiolological Imaging in Rhinology and Skull Base Surgery.

Volume 2. Paediatrics. Introduction to Paediatric Otorhinolaryngology. The Paediatric Consultation. Recognition and Management of the Sick Child. Anaesthesia for Paediatric Otorhinolarynglolgy Procedures. The Child with Special Needs. The Child with a Syndrome. Management of the Immunodeficient Child. Hearing Screening and Surveillance. Hearing Tests in Children. Investigation Management of Deaf Child. Congenital Middle Ear Abnormalities. Otitis Media with Effusion. Acute Otitis Media. Chronic Otitis Media. Microtia and External Ear Abnormalities . Speech and Language Development. Cleft Lip and Palate. Craniofacial Anomalies. Vertigo in Children. Facial Paralysis in Children. Epistaxis. Neonatal Nasal Obstruction. Rhinosinusitis and its Complications. Lacrimal Disorders in Children. The Adenoid and Adenoidectomy. Paediatric Obstructive Sleep Apnoea. Stridor. Acute Laryngeal Infections. Congenital Disorders of Larynx, Trachea and Bronchi. Acquired Laryngotracheal Stenosis. Juvenile-Onset Recurrent Respiratory Papillomatosis. Paediatric Voice Disorders. Foreign Bodies in the Ear, Nose and Throat. Tracheostomy and Home Care. Peri-Natal Airway Management. Cervicofacial Infections. Diseases of Tonsils, Tonsillectomy and Tonsillotomy. Salivary Glands. Tumours of Head and Neck. Cysts and Sinuses of Head and Neck. Haemangioma and Vascular Malformations. Drooling and Aspiration. Reflux and Eosinophilic Oesophagitis. Oesophageal Disorders in Children. Ear and Skull Base. AUDIO-VESTIBULAR MEDICINE. Anat and Embryol EXT + Middle Ear. The Anatomy of the Cochlea and Vestibular System: Relating Ultrastructure to Function. Physiology of Hearing. Physiology of Equilibrium. Perception of Sounds. Psychoacoustic Audiometry. Evoked Measurement of Auditory Sensitivity. Prevention of Hearing Loss. Hearing Aids. Beyond Hearing Aids: an Overview of Adult Audiological Rehabilitation. Age-Related Sensorineural Hearing Impairment . Noise Induced Hearing Loss and Related Conditions. Autosomal Dominant Nonsydromic SNHL. Ototoxicity. Idiopathic Sudden Sensorineural Hearing Loss. Tinnitus and Hyperacusis. Evaluation of Balance. Ménière’s Disease. Benign Paroxysmanl Positional Vertigo. Sup Semi Circular Canal Dehiscence. Vestibular Neuritis. Migrainous Vertigo. Vestibular Rehabilitation. Auditory Neuropathy Spectrum Disorder and Retrocochlear Disorders in Adults and Children. Understanding Tinnitus: A Psychological Perspective. Auditory Processing Disorders Across the Age Span. Psychiatric Aspects of Vestibular Disorders. OTOLOGY. Clinical Examination of Ears and Hearing. Furunculosis. Myringitis. Keratosis Obturans, Primary Auditory Canal Cholesteatoma and Benign Necrotizing Otitis Externa. Acquired Atresia of the External Ear. Otitis Externa and Otomycosis. Periochondritis of External Ear. Exostosis of the External Auditory Canal. Osteoradionecrosis of Temporal Bone. Acute Otitis Media in Adults. Chronic Otitis Media. Myringoplasty. Ossiculoplasty. Eustachian Tube Dysfunction. Otoendoscopy. Tuberculosis of Temporal Bone. Otosclerosis. Otological Effects of Paget's Disease. Ear Trauma. Otalgia. IMPLANTATION OTOLOGY. Bone Conduction Hearing Aids. Cochlear Implants. Middle Ear Implants. Auditory Brainstem Implant. SKULL BASE. Radiology of the Temporal Bone. Anatomy of the Lateral Skull Base. Evaluation of the Skull Base Patient. Vascular Assessment and Management. Natural History of Vestibular Schwannoma. Surgical Management of Vestibular Schwannoma. Gamma Knife. Patient with Neurofibromatosis 2. Non-Vestibular Schwannoma Tumours of the Cerebellopontine Angle. Middle Fossa Surgery. Jugular Foramen Lesions and their Management. Petrous Apex Lesions. Approaches to Nasopharynx and Eustachian Tube. Tumours of the Temporal Bone. Clinical Neuroanatomy. The Facial Nerve and its Non-Neoplastic Disorders. Tumours of the Facial Nerve. Osteitis of the Temporal Bone. Squamous Carcinoma of the Temporal Bone. Complications of Skull Base Surgery.

Volume 3. Head and Neck Surgery. History. Aetiology of Head and Neck Cancer. Epidemiology of Head and Neck Cancer. Staging of Head and Neck Cancer. The Changing Face of Cancer Information. Molecular Biology of Head and Neck Cancer. Nasal Cavity and Paranasal Sinus Malignancy. Nasopharyngeal Carcinoma. Benign Salivary Gland Tumours. Malignant Tumours of the Salivary Glands. Tumours of the Parapharyngeal Space. Oral Cavity Tumours Including the Lip . Oropharyngeal Tumours. Tumours of the Larynx. Rehabilitation after Total Laryngectomy. Management of Hypopharyngeal Cancer. Neck Metastases from an Unknown Primary. Metastatic Neck Disease. Principles and Practice of Radiotherapy in Head and Neck Cancer. Quality of Life and Survivorship in Head and Neck Cancer. Palliative Care for Head and Neck Cancer. Transoral Laser Microsurgery. Transoral Anatomy as Applied to Transoral Surgery. Chemotherapy in Head and Neck Cancer. Cysts and Tumours of the Bony Facial Skeleton. Pathology of Head and Neck Malignancies. Open Conservation Surgery for Laryngeal Cancer. Measures of Treatment Outcomes. Applications of Robotics in Head and Neck Practice. Biologically Targeted Agents in Head and Neck Cancer. Prosthetic Rehabilitation of HN Defects. Multidisciplinary Team Working. Nutritional Considerations in Head and Neck Cancer. Speech, Voice and Swallow Rehabilitation after Chemoradiation. Surgical Anatomy of the Neck. Clinical Examination of the Neck. Imaging of the Neck. Neck Trauma. Benign Neck Disease. Neck Space Infections. Anatomy and Embryology of the Mouth and Dentition. Benign Oral and Dental Disease. Salivary Gland Anatomy. Physiology of the Salivary Glands. Imaging of the Salivary Glands. Non-Neoplastic Salivary Gland Diseases. Anatomy of the Pharynx and Oesophagus. Physiology of Swallowing. Causes and Assessment of Dysphagia and Aspiration. Functional Investigations of the Upper Gastrointestinal Tract. Pharyngitis. Cricopharyngeal Dysphagia. Oesophagal Diseases. Neurological Disease of the Pharynx. Rehabilitation of Swallowing Disorders. Chronic Aspiration. Temporomandibular Joint Disorders. Anatomy of the Larynx and Tracheobronchial Tree. Physiology of the Larynx. Voice and Speech Production. Assessment and Examination of the Larynx. Evaluation of the Voice. Structural Disorders of the Vocal Chords. Functional Disorders of the Voice. The Professional Voice. Speech/Voice Therapy for Voice Disorders. Phonosurgery. Movement Disorders of the Larynx. Acute Infections of the Larynx. Chronic Laryngitis. Contemporary Management of Laryngotracheal Trauma. Upper Airway Obstruction and Tracheostomy. Physiology of Sleep and Sleep Disorders. Obstructive Sleep Apnoea: Medical Management. The Surgical Management of Snoring. Laryngeal Stenosis in Adults. Reflux Disease. Paralysis of the Larynx. Outpatient Laryngeal Procedures. Plastic Surgery. Rhinoplasty Following Nasal Trauma. Pre-Operative Assessment for Rhinoplasty. External Rhinoplasty. Revision Rhinoplasty. Aesthetic Dorsal Reduction in Rhinoplasty. Nasal Reconstruction. Pinnaplasty. Blepharoplasty. Surgical Rejuvenation of the Ageing Face. Non-Surgical Rejuvenation of the Ageing Face. History of Reconsctructive Surgery. Grafts and Local Flaps in Head and Neck Surgery. Pedicle Flaps in Head and Neck Reconstruction. Reconstructive Microsurgery in Head and Neck Surgery. Benign and Malignant Conditions of the Skin. Facial Reanimation Surgery. Partial and Total Ear Construction. A Combined Prosthetic and Surgical Approach to Head and Neck Reconstruction.