Drug Disposition and Pharmacokinetics (eBook)

Stephen H. Curry is an independent consultant, teacher and writer. With extensive experience of academia and the pharmaceutical industry, he is Professor of Pharmacology and Physiology at the University of Rochester, having held appointments at the University of London, the University of Florida, and with Fisons and AstraZeneca. He has written 4 books and over 150 publications in scientific journals, including prize-winning papers and essays. He was the founding co-editor of the Wiley-Blackwell Journal Biopharmaceutics and Drug Disposition. Robin Whelpton is a senior lecturer at Queen Mary University of London with over thirty years teaching experience. He has written and contributed to a number of books, including co-authoring the successful Fundamentals of Analytical Toxicology published by Wiley-Blackwell in 2008, and published extensively in scientific and technical journals.

"Although there are numerous books on pharmacokinetics, the
broad scope and thorough coverage of this one make it an excellent
choice, either for a formal class or for self-study.

Each topic is carefully presented, from the simplest starting
point through increasing levels of complexity.

The text provides a unique, balanced approach, examining the
specific physical and biological factors affecting the absorption,
distribution, metabolism and excretion of drugs, together with
mathematical assessment of the concentrations in plasma and body
fluids.

This readable and informative book is an invaluable resource for
professionals and students needing to develop a rational approach
to the investigation and application of drugs.

The broad scope of this book is intended to support its use by
undergraduate, graduate, and professional students new to the
field, but also by even experienced biomedical scientists and
healthcare professionals as a refresher and reference. These are
ambitious goals. The breadth and depth of the treatment of
disposition and pharmacokinetics clearly meets the latter goal.

All the above quotes are from (Doody's, 28
October 2012)

"The book provides a good breadth of knowledge, and readers will
not be overwhelmed by unnecessary detail. For example, complex
scientific and mathematical models are conveyed in a remarkably
understandable manner that underpin the relevant topic rather than
distracts from it. Nineteen chapters are presented in a logical
sequence, each with a consistent structure and a number of
different subheadings. Up-to-date and relevant references are
offered at the end of each chapter, and there is a comprehensive
index that is sufficiently detailed to allow readers to easily
locate subject topics or worked examples . . .I would have found
this book invaluable at an earlier stage of my own career, and
consider it to be highly relevant to those engaged in research in
either a pharmaceutical industry or academic setting. Drug
Disposition and Pharmacokinetics will appeal to students from a
range of scientific disciplines including medicine, toxicology,
pharmacology and pharmacy. Whilst it is primarily suited to those
at a postgraduate or post-doctoral level, it will also be of
interest to undergraduates seeking a deeper knowledge than offered
by less authoritative compact textbooks." (The British Toxicology
Society, 1 May 2011)

"This is an authoritative, comprehensive book on the fate of
drug molecules in the body, including implications for
pharmacological and clinical effects". (HPC Market Watch, 19
January 2011)