Evolution of Virulence in Eukaryotic Microbes (eBook)
584 Seiten
John Wiley & Sons (Verlag)
978-1-118-30813-4 (ISBN)
Evolution of Virulence in Eukaryotic Microbes addresses new developments in defining the molecular basis of virulence in eukaryotic pathogens. By examining how pathogenic determinants have evolved in concert with their hosts, often overcoming innate and adaptive immune mechanisms, the book takes a fresh look at the selective processes that have shaped their evolution.
Introductory chapters ground the reader in principal evolutionary themes such as phylogenetics and genetic exchange, building a basis of knowledge for later chapters covering advances in genetic tools, how pathogens exchange genetic material in nature, and the common themes of evolutionary adaptation that lead to disease in different hosts.
With the goal of linking the research findings of the many disparate scientific communities in the field, the book:
* Assembles for the first time a collection of chapters on the diversity of eukaryotic microorganisms and the influence of evolutionary forces on the origins and emergence of their virulent attributes
* Highlights examples from three important, divergent groups of eukaryotic microorganisms that cause disease in animals and plants: oomycetes, protozoan parasites, and fungi
* Covers how the development of genetic tools has fostered the identification and functional analyses of virulence determinants
* Addresses how pathogens exchange genetic material in nature via classical or modified meiotic processes, horizontal gene transfer, and sexual cycles including those that are cryptic or even unisexual
* Provides a broad framework for formulating future studies by illustrating themes common to different pathogenic microbes
Evolution of Virulence in Eukaryotic Microbes is an ideal book for microbiologists, evolutionary biologists and medical professionals, as well as graduate students, postdoctoral fellows, and faculty members working on the evolution of pathogens.
Dr. David Sibley, PhD, is a faculty member at the Washington University School of Medicine, where he teaches graduate courses in microbiology and has served on the steering committee for the Molecular Microbiology program for the past 10 years. In addition to authoring over 150 publications,?Dr. Sibley is an associate editor for PLoS Pathogens, edits reviews for Cellular Microbiology, and serves on the board of reviewing editors for Science. Dr. Barbara Howlett, PhD, is a Professor in the School of Botany at the University of Melbourne, specializing in fungal diseases of plants. She serves in an editorial capacity for PLoS Pathogens, Eukaryotic Cell, and the European Journal of Plant Pathology. Dr. Joseph Heitman, MD, PhD is currently Chair of the Dept of Molecular Genetics and Microbiology at Duke University. Dr. Heitman has co-authored four other books on the topics of eukayrotic function and pathogenesis, and serves as an editor for numerous?publication includingEukaryotic Cell, Virulence, and the Journal of Molecular Medicine.
General Overviews
1) Population genetics and parasite diversity
Hsiao-Han Chang, Rachel F. Daniels and Daniel L. Hartl
2) Evolution of Meiosis, Recombination, and Sexual Reproduction in Eukaryotic Microbes
Wenjun Li, Elizabeth Savelkoul, Joseph Heitman and John M. Logsdon, Jr.
3) Phylogenomic Analysis
Andrew J. Roger, Martin Kolisko and Alastair G. B. Simpson
4) Phylogenetics and Evolution of Virulence in the Kingdom Fungi
Arturo Casadevall and Monica A. Garcia-Solache
Population genetics and evolutionary approaches
5) Malaria: Host Range, Diversity and Speciation
Ananias A. Escalante and Francisco J. Ayala
6) From Population Genomics to Elucidated Traits in Plasmodium falciparum
Daniel E. Neafsey, Stephen F. Schaffner, Pardis C. Sabeti, Sarah K. Volkman and Dyann F. Wirth
7 Selective sweeps in human malaria parasites
Xin-zhuan Su and John C. Wootton
8) Evolution of Drug Resistance in Fungi
Jessica A. Hill, Samantha J. Hoot, Theodore C. White and Leah E. Cowen
9) Discovery of extant sexual cycles in human pathogenic fungi and their roles in the generation of diversity and virulence
Richard J. Bennett and Kirsten Nielsen
10) Worldwide migrations, host shifts and re-emergence of Phytophthora infestans, the Plant
Destroyer
Jean Beagle Ristaino
11) Experimental and natural evolution of the Cryptococcus neoformans and C. gattii species complex
Alexander Idnurm and Jianping Xu
12) Population genetics, diversity and spread of virulence in Toxoplasma gondii
Benjamin M. Rosenthal and James W. Ajioka
Forward and reverse genetic systems for defining virulence
13) Genetic Crosses for Plasmodium falciparum: analysis of drug resistance
John C.Tan and Michael Ferdig
14) Genetic mapping of virulence in rodent malarias
Richard Carter and Richard Culleton
15) Genetic Mapping of Acute Virulence in Toxoplasma gondii
L. David Sibley and John C. Boothroyd
16) Virulence in African trypanosomes: genetic and molecular approaches
Annette MacLeod , Liam J. Morrison and Andy Tait
17) The evolution of antigenic variation in African trypanosomes
Andrew P. Jackson and J. David Barry
18) Antigenic Variation, Adherence and Virulence in Malaria
Joseph Smith and Kirk Deitsch
19) Invasion Ligand Diversity and Pathogenesis in Blood-Stage Malaria
Manoj T. Duraisingh, Jeffrey D. Dvorin and Peter Rainer Preiser
Comparative "omics" approaches to defining virulence
20) Evolution of Virulence in Oomycete Plant Pathogens
Paul R. J. Birch, Mary E. Coates and Jim L. Beynon
21) Evolution and genomics of the pathogenic Candida species complex
Geraldine Butler, Mike Lorenz and Neil A. R. Gow
22) Evolution of Entamoeba histolytica virulence
Upinder Singh and Christopher D. Huston
23) Sex and Virulence in Basidiomycete Pathogens
Guus Bakkeren, Emilia K. Kruzel and Christina M. Hull
24) Emergence of the chytrid fungus Batrachochytrium dendrobatidis and global amphibian declines
Matthew C. Fisher, Jason E. Stajich and Rhys A. Farrer
25) Impact of Horizontal Gene Transfer on Virulence of Fungal Pathogens of Plants
Barbara J. Howlett and Richard P. Oliver
26) Evolution of plant pathogenicity in Fusarium species
Li-Jun Ma, H. Corby Kistler and Martijn Rep
27) Genetic, genomic, and molecular approaches to define virulence of Aspergillus fumigatus
Laetitia Muszkieta,, William J. Steinbach and Jean-Paul Latge
28) Cryptosporidium: comparative genomics and pathogenesis
Satomi Kato and Jessica C. Kissinger
"It should be of interest to evolutionary biologists,
medical microbiologists and plant pathologists at postdoctoral and
faculty levels." (Microbiology Today, 26
November 2012)
Erscheint lt. Verlag | 7.6.2012 |
---|---|
Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Gesundheitsfachberufe |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin | |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Technik | |
Schlagworte | Biowissenschaften • Infectious Disease & Microbiology • Infektionskrankheiten u. Mikrobiologie • Life Sciences • Medical Science • Medizin • Microbiology & Virology • Mikrobiologie • Mikrobiologie u. Virologie • Molecular Evolution • Molekulare Evolution • Virologie |
ISBN-10 | 1-118-30813-1 / 1118308131 |
ISBN-13 | 978-1-118-30813-4 / 9781118308134 |
Haben Sie eine Frage zum Produkt? |
![EPUB](/img/icon_epub_big.jpg)
Größe: 8,8 MB
Kopierschutz: Adobe-DRM
Adobe-DRM ist ein Kopierschutz, der das eBook vor Mißbrauch schützen soll. Dabei wird das eBook bereits beim Download auf Ihre persönliche Adobe-ID autorisiert. Lesen können Sie das eBook dann nur auf den Geräten, welche ebenfalls auf Ihre Adobe-ID registriert sind.
Details zum Adobe-DRM
Dateiformat: EPUB (Electronic Publication)
EPUB ist ein offener Standard für eBooks und eignet sich besonders zur Darstellung von Belletristik und Sachbüchern. Der Fließtext wird dynamisch an die Display- und Schriftgröße angepasst. Auch für mobile Lesegeräte ist EPUB daher gut geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen eine
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen eine
Geräteliste und zusätzliche Hinweise
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich