Cancer Gene Therapy
Kluwer Academic/Plenum Publishers (Verlag)
978-0-306-46191-0 (ISBN)
The Clinical Problem.- Management Problems in Oncology.- Vectors.- Adenoviral Vectors.- Retrovirus Vectors.- Targetable Gene Delivery Vectors.- Human ?-fetoprotein Transcriptional Regulatory Sequences.- Tumor-Targeted Salmonella.- Mutant Adenoviruses Selectively Replication-Competent in Tumor Cells.- Polyoma and Papilloma Virus Vectors For Cancer Gene Therapy.- Cochleates.- The Use Of Skeletal Muscle To Express Genes For The Treatment Of Cancer.- Cell Cycle Control.- Adhesion Molecules in Cancer Biology.- Cell Cycle Control.- Apoptosis.- Killer/DR5, A Novel DNA-Damage Inducible Death Receptor Gene, Links the p53-Tumor Suppressor to Caspase Activation and Apoptotic Death.- Apoptin®.- Adenovirus-Mediated Herpes Simplex Thymidine Kinase Gene Therapy For Brain Tumors.- Development of Clinical Trial of E1A Gene Therapy Targeting HER-2/neu-overexpressing Breast and Ovarian Cancer.- Tumout Suppressor Genes.- Pre-clinical Studies with Tumor Suppressor Genes.- Gene Therapy for Liver Tumours.- Adenovirus-mediated Transfer of a p53 Gene in Ovarian Cancer.- Other Systems.- Eliciting Hyperacute Rejection as a Tumor Killing Strategy.- Innate Immune Therapy For Cancer.- Mda-7, A Novel Melanoma Differentiation Associated Gene with Promise for Cancer Gene Therapy.- Antisense and Ribozymes.- Antisense IGF and Antisense IGF-IR Therapy of Malignancy.- Sensitization of Tumors to Chemotherapy Through Gene Therapy.- Design and Testing of Ribozymes for Cancer Gene Therapy.- Ribozymes.- The Approach of Triple Helix Formation in Control of Gene Expression and The Treatment of Tumors Expressing IGF-I.- Immuno-Modulation.- Dendritic Cell-based Immunization for Cancer Therapy.- Hybrid Cell Vaccination for Cancer Immunotherapy.- Modulation of the Immune Response Through 4-1BB.- Heat Shock Proteinsin Cancer Therapy.- Bi-Specific Antibodies in Cancer Therapy.- B7.1 and Cytokines.- Intralesional Vaccinia/GM-CSF Recombinant Virus in the Treatment of Metastatic Melanoma.- Suicidal Genes.- Approaches to Gene-Directed Enzyme Prodrug Therapy (GDEPT).- Suicide Gene Therapy.- Adenoviruses as Gene Delivery Vectors.- Angiogenesis Control.- Evaluation of an Inhibitor of DNA Methylation, 5-aza-2?-Deoxycytidine, for The Treatment of Lung Cancer and the Future Role of Gene Therapy.- Vascular Endothelial Growth Factor as a Target for Cancer Gene Therapy.- Adeno-Associated Virus and Other Potential Vectors for Angiostatin and Endostatin Gene Therapy.- Matrix Metallo Proteinase.- Potential Applications of Tissue Inhibitor of Metalloproteinase (TIMP) Overexpression For Cancer Gene Therapy.
Erscheint lt. Verlag | 30.4.2000 |
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Reihe/Serie | Advances in Experimental Medicine and Biology ; 465 |
Zusatzinfo | XVI, 496 p. |
Sprache | englisch |
Maße | 156 x 234 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
ISBN-10 | 0-306-46191-9 / 0306461919 |
ISBN-13 | 978-0-306-46191-0 / 9780306461910 |
Zustand | Neuware |
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