Toxicology and Human Environments

Dr Ernest Hodgson, Distinguished Professor Emeritus, North Carolina State University and Executive Director, Foundation for Toxicology and Agromedicine was educated at King’s College of the University of Durham (now the University of Newcastle), Oregon State University and the University of Wisconsin. At North Carolina State University since 1961 he was a William Neal Reynolds Professor and Head of the newly formed Department of Toxicology. He was also one of the founders of the three university (East Carolina University, North Carolina State University and North Carolina A&T University) program in agromedicine, an organization which led to the formation of the North Carolina Agromedicine Institute. Dr. Hodgson has conducted research on xenobiotic biochemistry for several decades, has authored c. 400 peer-reviewed papers in this area, and is editor and part author of several monographs. Most recently his research has focused on human studies utilizing human hepatocytes and sub-cellular preparations. Currently involved as a collaborator with Dr Michael Roe in RNAseq studies of genome-wide effects of environmental chemicals. From 1961 until his retirement he was supported by extramural funding, primarily from NIH (NIEHS) and the US Army. Dr Hodgson is also editor and contributing author of toxicology textbooks (Textbook of Modern Toxicology and Molecular and Biochemical Toxicology, both currently in their 4th editions) and is a lexicographer (Dictionary of Toxicology, under revision for a 3rd edition and a Dictionary of Agromedicine, being created for the NC Agromedicine Institute). He is well recognized for his role as a teacher of toxicology. In addition to his role as editor and part author of textbooks he has trained some 40 graduate students and 20 post-doctoral research associates. His service on federal study sections and other federal panels has been extensive and includes the following agencies. NIH, NASA, US Army and others. He has been recognized by awards from the Society of Toxicology, the American Chemical Society, the International Society for the Study of Xenobiotics, the Consolidated University of North Carolina and North Carolina State University. He is a past president of the International Society for the Study of Xenobiotics.

Human Environments: Definition, Scope and the Role of Toxicology
Ernest Hodgson

Estimating Human Exposure: Improving Accuracy with Chemical Markers
Roger C. Cochran and Jeffrey H. Driver

Metabolism of Xenobiotics Human Environments
Edward Croom

Toxic Endpoints in the Study of Human Exposure to Environmental Chemicals
Andrew D. Wallace

Pesticide Regulations: Exposure-Dose Modeling from FIFRA to FQPA
James B. Knaak, Cecilla Tan and Curt C. Dary

Occupational Chemicals: Metabolism, Toxicity and Mode of Action
Sheila Flack and Leena A. Nylander-French

Chemicals of Military Deployments: Revisiting Gulf War Syndrome in Light of New Information
A.A. Brimfield

Pharmaceuticals in the Environment: Lessons Learned for Reducing Uncertainties in Environmental Risk Assessment
Bryan W. Brooks, Jason P. Berninger, Lauren A. Kristofco, Alejandro J. Ramirez, Jacob K. Stanley and Theodore W. Valenti

Quantitative Risk Assessment Methods for Cancer and Non-Cancer Effects
Ronald E. Baynes

Human Health Risk Assessment for Contaminated Properties
Atul M. Salhotra

The Future of Human Health Risk Assessment of Environmental Chemicals.
Ernest Hodgson

Ecological Risk Assessment
Damian Shea and Waverly Thorsen

Metabolic Interactions of Environmental Toxicants in Humans
Ernest Hodgson

Toxins and Venoms
Ernest Hodgson

Summary and Conclusions

Ernest Hodgson