Bradykinin, Kallidin and Kallikrein

1: Introduction.- Discovery of the Most Important Kallikreins and Kallikrein Inhibitors.- The Discovery and Characterization of Bradykinin.- 2: Methods Used in Kinin Research.- The Kinins: Methods of Chemical Synthesis.- Purification of Mammalian Kallikreins, Kininogens, and Kinins.- Assay Methods in the Kinin System.- 3: Kininogenases.- Plasma Kininogenases and Their Activators.- Kallikreins in Glandular Tissues.- Proteolytie Enzymes as Kininogenases.- Snake Venoms.- Kallikrein Inhibitors.- 4: Kininogens.- Kininogens.- 5: Kininases.- Kininases.- 6: Kinins.- Section A: Physiological and Pharmacological Actions.- Structure-Activity Relationships of Kinins.- Effect of Kallikrein on the Cardiovascular System.- The Effect of the Kinins on the Cardiovascular System.- Effects of Bradykinin on the Kidney and Gastrointestinal Organs.- The Physiological Role of Glandular Kallikreins.- Vasodilatation in the Submaxillary Gland of the Cat, Rabbit, and Sheep.- Kinins and Ventilation of the Lungs.- The Effect of Bradykinin and Kallidin on Smooth Muscle.- Effect of Bradykinin on the Central Nervous System.- Section B: Pathological Role.- Pain.- Bradykinin and Intracranial Circulation in Man.- Kinins in Inflammation and Tissue Injury.- Immunochemistry of Bradykinin and Immunologic Activation of the Kinin System.- Addenda.- Evaluation of the Role of Kinins in Experimental, Pathological, and Clinical Conditions; the Therapeutic Use of Kallikrein Inhibitor.- 7: Urinary Kinins.- Urinary Kinins and Colostrokinin.- 8: Non-Mammalian Kinins.- Discovery of Non-Mammalian Kinins.- Kinins of Non-Mammalian Origin.- 9: Summary of Literature Published in Various Languages.- Summary of the Literature Published in Czechoslovakian, Polish, and Russian Journals.- A Summary of Literature Published in French.- Summary of Literature Published in Italian.- Summary of Literature Published in Japanese.- Summary of Literature Published in Spanish and Portuguese.- Author Index.