Experimental Production of Diseases

Experimental Hepatotoxicity.- A. Introductory Considerations.- B. Historical Aspects.- C. Relevance of Experimental Hepatotoxicity.- D. Vulnerability of the Liver to Toxic Injury.- E. Types of Experimental Models.- F. Types of Toxic Hepatic Injury.- G. Classification of Hepatotoxins.- H. Direct Hepatotoxins.- I. Indirect Hepatotoxins.- K. Concluding Comments.- Appendix. Meaning of Abbreviations.- References.- Liver Disease Due to Infection and Allergy.- A. Introduction.- B. Liver Disease Due to Infection.- C. Classical Human Viral Hepatitis.- D. Liver Disease Associated with Autoimmune Reactions.- E. Experimental Models of Chronic Hepatitis.- F. Liver Diseases Associated with Drug Reactions.- G. Conclusion: Immunology and the Liver.- Abbreviations.- References.- Radiation-Induced Injury of the Liver.- A. Introduction.- B. Preliminary Remarks.- C. Radiation-Induced Changes of the Human Liver.- D. Experimental Investigations of the Radiation Effect.- Abbreviations.- References.- Experimental Production of Gallstones.- A. A Fat- and Cholesterol-Free Diet in Hamsters.- B. A Lithogenic Diet Supplemented with Chenodeoxycholic Acid.- C. A High Cholesterol Diet in Prairie Dogs.- D. A Diet Supplemented with D-Thyroxine in Hamsters.- E. A Fat-and Cholesterol-Rich Diet in Squirrel Monkeys.- Abbreviations.- References.- Author Index.