Pharmacology of Fluorides

1: Methods of Analysis for Fluorine.- I. Introduction.- II. Methods of Sample Preparation.- III. Methods of Separation.- IV. The Detection of Fluoride.- V. The Determination of Fluoride.- VI. The Determination of Common Elements in Organic Fluorine Compounds.- References.- 2: Effect of Inorganic Fluoride on Enzymes.- I. General Introduction.- II. Enzymes, Inhibited by Fluoride, Requiring Metal Ions, and Whose Inhibition is Enhanced by Phosphate.- III. Enzymes, Inhibited by Fluoride, Requiring Divalent Metal Ions.- IV. Enzymes Inhibited by Fluoride; No Requirement for Metal Ions Demonstrated.- V. Enzymes, Inhibited by Fluoride, Containing Trivalent Metal Ions.- VI. Concluding Comments.- References.- 3: Changes in Cell Function Due to Inorganic Fluoride.- I. Introduction.- II. Effect of Fluoride on Metabolic Pathways.- III. Effects of Fluoride on Physical Activity of Cells.- IV. Effects of Fluoride on the Growth and Development of Cells in Tissue Culture.- V. Concluding Remarks.- References.- 4: Pharmacology of Sodium Fluoride.- I. Introduction.- II. Effect of Sodium Fluoride on Blood Pressure and the Heart.- III. Effect of Sodium Fluoride on the Gut.- IV. Effect of Sodium Fluoride on Respiration.- V. Summary and Conclusions.- References.- 5: Fluoroamino Acids and Microorganisms.- I. Introduction.- II. Fluoroamino Acids and Cellular Microorganisms.- References.- 6: Fluorine-Containing Steroids.- I. Introduction.- II. Fluoro Steroids with Respect to Glucogenic, Anti-Inflammatory and Mineralocorticoid Effect.- III. Fluoro-Steroids with Respect to Gestagenic, Anti-Androgenic, Anti-Estrogenic, Anti-Ovulatory, and Anti-Gonadotrophic Effects.- IV.Fluoro-Steroids with Respect to Androgenic, Anabolic, Anti-Androgenic, Anti-Tumor and Anti-Gonadotropic Effect.- V. Fluoro-Steroids with Respect to Estrogenic, Hypocholesterolemic, Anti-Gonadotropic and Anti-Tumor Effects.- VI. Fluoro Steroids with Respect to Anti-Mineralocorticoid Effect.- VII. Anti-Cancer Effects of Fluoro Steroids.- VIII. Structure-Activity Relationships and Influence of Fluorination.- IX. Other Fluoro-Steroids.- References.- 7: Biological Properties of Selected Fluorine-Containing Organic Compounds.- I. Introduction.- II. The Carbon-Fluorine Bond.- III. Metabolism of Organic Fluoroeompounds.- IV. Biological Effects of Organic Compounds of Fluorine.- References.- Author Index.