Apoptosis

An Endonuclease Responsible for Apoptosis.- 1 Introduction.- 2 Results.- 3 Discussion.- References.- Cytopathic Feline Leukemia Viruses Cause Apoptosis in Hemolymphatic Cells.- Abstract.- 1 Introduction.- 2 Cytopathic Infections with FeLV-C in Vivo and Direct Induction of Apoptosis in T4 Cells by FeLV-C.- 3 Killing of Lymphocytes by FeLV-FAIDS/p61C and Associated Variants.- 4 FeLV-C-Related Nonregenerative Anemia: Potential Role for Apoptosis.- 5 FeLV Genes Important in Cytopathicity/Apoptosis Induction.- 6 Speculative Relationship to Endogenous Virus Recombinants and Importance Across Evolution.- 7 Regions of FeLV p15E Important in Immunosuppression.- 8 Other Types of Cytopathic Disease Seen in Viremic Cats Which Could Have an Apoptotic Basis.- 9 So How Does FeLV Cause Apoptosis?.- 10 Other Retroviruses and Animal Viruses as Potential Causes of Apoptosis.- References.- Neurotoxicity in Rat Cortical Cells Caused by N-Methyl-D-Aspartate (NMDA) and gp120 of HIV-1: Induction and Pharmacological Intervention.- Abstract.- 1 Introduction.- 2 Induction of Apoptosis in Rat Cortical Cells by HIV-1 gp120 or NMDA In Vitro.- 3 Prevention of Apoptosis in Cortical Cells In Vitro by Memantine and Flupirtine.- 4 Conclusion.- References.- Apoptosis of Mature T Lymphocytes: Putative Role in the Regulation of Cellular Immune Responses and in the Pathogenesis of HIV Infection.- Abstract.- 1 Apoptosis of Immature T Lymphocytes.- 2 Apoptosis of Mature T Lymphocytes.- 3 Apoptosis of T Lymphocytes Induced by Superantigens and Conventional Antigen.- 4 Apoptosis of Mature T Lymphocytes In Vivo and Ex Vivo.- 5 Role of T-Cell Apoptosis in HIV Pathogenesis.- 6 Concluding Remarks.- References.- bcl-2: Antidote for Cell Death.- Abstract.- 1 Introduction.- 2 Structure and Expression of the bcl-2 Gene.- 3 Biological Function of bcl-2: Apoptotic Death-Sparing Activity.- 4 Role of bcl-2 in the Immune System.- 5 Role of bcl-2 in Neuronal Tissue.- 6 Role of bcl-2 in Lymphomagenesis.- 7 Role of bcl-2 in Other Systems.- 8 Analysis of bcl-2-Deficient Mice.- 9 Subcellular Localization of bcl-2: Multiple Membrane Locations.- 10 Biochemical Function of bcl-2 Protein.- 11 bcl-2 Related Genes and bcl-2 Associated Proteins.- 12 Epilogue.- References.- Apoptosis Mediated by the Fas System.- Abstract.- 1 Introduction.- 2 Fas, a Receptor for a Death Factor.- 3 Mutation in the Fas Gene of lpr-Mice.- 4 Fas-Mediated Apoptosis.- 5 Fas Ligand, a Death Factor.- 6 Physiological Roles of the Fas System.- 7 Perspectives.- References.- Myc-Mediated Apoptosis.- Abstract.- 1 Introduction.- 2 c-Myc-Mediated Apoptosis.- 3 s-Myc-Mediated Apoptosis.- 4 Escape from Myc-Induced Apoptotic Cell Death.- 5 Conclusions.- References.- Clusterin: A Role in Cell Survival in the Face of Apoptosis?.- Abstract.- 1 Introduction.- 2 Clusterin-a Widely Expressed Multifunctional Protein.- 3 Clusterin Gene Expression in Apoptotic Epithelial Tissues.- 4 Clusterin Gene Expression in the Thymus.- 5 Clusterin Gene Expression in Retinitis Pigmentosa (RP) Retina.- 6 Clusterin Expression During Degenerative Processes in the Brain.- 7 Conclusions and Perspectives.- References.