Principles and Treatment of Lipoprotein Disorders

Gotthard Schettler, Andreas J.R. Habenicht (Herausgeber)

Buch | Softcover

XXIII, 502 Seiten

2011 | 1. Softcover reprint of the original 1st ed. 1994
Springer Berlin (Verlag)
978-3-642-78428-6 (ISBN)

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Major advances have been made in the understanding of the molecular mechanisms of atherosclerosis, the disease that still affects more than 50 percent of the population in the highly industrialized countries. This volume covers the most recent advances in the treatment of hyperlipidemia. It represents a necessary update because molecular mechanisms of atherogenesis have been discovered in the past few years and their molecular mechanisms of action identified. Extensively treated are the molecular mechanisms of disease etiology of arteriosclerosis in relation to the major risk factor "hyperlipidemia", rationale for more effective treatment of this disease by dietary means, the treatment of associated or causing diseases, and the treatment using hypolipidemic drugs.

Section A: Physiology and Pathophysiology of Lipid Metabolism.- 1 An Introduction to the Biochemistry and Biology of Blood Lipids and Lipoproteins.- 2 Lipoprotein Metabolism.- 3 Lipoprotein Receptors.- 4 Genetic Disorders of Lipoprotein Metabolism.- 5 Interactions Between Lipoproteins and the Arterial Wall.- 6 Lipoprotein Lipase and Hepatic Lipase.- 7 Animal Models of Lipoprotein Metabolism.- Section B: Lipid Lowering Therapy.- 8 Rationale to Treat.- 9 The Dietary Therapy of Hyperlipidemia: Its Important Role in the Prevention of Coronary Heart Disease.- 10 Lipid Apheresis.- Section C: Lipid Lowering Drugs.- 11 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors.- 12 Fibrates.- 13 Nicotinic Acid and Derivatives.- 14 Ion Exchange Resins.- 15 Probucol.- 16 Miscellaneous Lipid-Lowering Drugs.

Erscheint lt. Verlag	16.12.2011
Reihe/Serie	Handbook of Experimental Pharmacology
Co-Autor	D.H. Blankenhorn, H.B. Brewer, G.A. Coetzee, S.L. Connor, W.E. Connor, J. Davignon, A. Gaw, Albrecht J.R. Habenicht, E.v. Hodenberg, H.N. Hodis, D.R. Illingworth, U. Janßen-Timmen, D. Kritchevsky, K.J. Lackner, H.J. Menzel, G. Olivecrona, T. Olivecrona, A.G. Olsson, C.J. Packard, J.R. Patsch, W.O. Richter, P.B. Salbach, E.B. Schmidt, P. Schwandt, D. Seidel, J. Shepherd, G. Utermann, W.J.S.de Villiers, D.R.van der Westhuyzen
Zusatzinfo	XXIII, 502 p.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	790 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Medizin / Pharmazie ► Pharmazie
Schlagworte	Arterienverkalkung • Arteriosclerosis • atherogenesis • atherosclerosis • Cardiovascular Disease • Dietary Intervention • hepatology • Herzkrankheit • Hyperlipidemia • Hyperlipoproteinämie • Lipide • Lipid Lowering Drugs • lipoprotein • Protein • vascular disease
ISBN-10	3-642-78428-3 / 3642784283
ISBN-13	978-3-642-78428-6 / 9783642784286
Zustand	Neuware