Ruthenium and Other Non-Platinum Metal Complexes in Cancer Chemotherapy

With contributions by numerous experts

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Contents/Information: N.P. Johnson, J.-L. Butour, G. Villani, F.L. Wimmer, M. Defais, V. Pierson, Toulouse, France; V. Brabec, Kralovopolska, CSSR: Metal Antitumor Compounds: The Mechanism of Action of Platinum Complexes Pertaining to the Design of Anticancer Agents B.K. Keppler, M. Henn, U.M. Juhl, M.R. Berger, R. Niebl, Heidelberg; F.E. Wagner, Garching, FRG: New Ruthenium Complexes for the Treatment of Cancer G. Mestroni, E. Alessio, Trieste, M. Calligaris, Pavia, Italy; W.M. Attia, Ismailia, Egypt; F. Quadrifoglio, S. Cauci, Udine, Italy; G. Sava, S. Zorzet, S. Pacor, C. Monti-Bragadin, M. Tamaro, L. Dolzani, Trieste, Italy: Chemical, Biological and Antitumor Properties of Ruthenium (II) Complexes with Dimethylsulfoxide N. Farrell, Burlington/VT, USA: Metal Complexes as Radiosensitizers S.C. Srivastava, L.F. Mausner, M.J. Clarke, Upton/NY, and Chestnut Hill/MA, USA: Radioruthenium-Labeled Compounds for Diagnostic Tumor Imaging P. Köpf-Maier, Berlin, FRG: The Antitumor Activity of Transition and Main-Group Metal Cyclopentadienyl Complexes E.V. Scott, G. Zon, L.G. Marzilli, Atlanta/GA and Foster City/CA, USA: NMR Relaxation Footprinting: The ÄCr(NH3)6Ü3+ Cation as a Probe for Drug Binding Sites on Oligonucleotides J.E. Schurig, H.A. Meinema, K. Timmer, Wallingford/CT, USA; B.H. Long, A.M. Casazza, Zeist, NL: Antitumor Activity of BisÄBis(Diphenylphosphino)Alkane and AlkeneÜ Group VIII Metal Complexes M.E. Heim, H. Flechtner, Mannheim; B.K. Keppler, Heidelberg, FRG: Clinical Studies with Budotitane - A New Non-Platinum Metal Complex for Cancer Therapy