Structure and Control of the Melanocyte -

Structure and Control of the Melanocyte

Sixth International Pigment Cell Conference sponsored by The International Union Against Cancer

G. Della Porta, O. Mühlbock (Herausgeber)

Buch | Softcover
XVI, 374 Seiten
2012 | 1. Softcover reprint of the original 1st ed. 1966
Springer Berlin (Verlag)
978-3-642-99908-6 (ISBN)
106,99 inkl. MwSt
The first five International Pigment Cell Conferences have all been held in U.S.A., from 1948 to 1961. The late MYRON GORDON (1899-1959), was one of their initiators and was the person who was able to give a skillful continuity to these Conferences which have permitted a gathering together of the multiple aspects of investigations in pigment cell biology, including the clinical problem of melanomas. During the International Cancer Congress in Moscow, in 1962, mem bers of the Oncological Research Institute in Sofia offered to organize the Sixth Pigment Cell Conference. Because of their interest and experience in the field of experimental and human melanomas, this seemed highly appropriate. The International Union Against Cancer agreed to sponsor the Conference, since one of the final goals of studies in pigment cell bio logy is certainly the control of the neoplastic deviation of the melanocyte. Thus, for the first time, the Pigment Cell Conference was held in Europe. After discussions with various investigators, the Program Com mittee decided to limit somewhat the chemical and biological part of the program in order to allow relatively more space to electron microscopy of the melanocyte, biology of experimental melanomas, and epidemiology and clinical aspects of human melanomas.

Terminology of Vertebrate Melanin-Containing Cells, Their Precursors, and Related Cells: A Report of the Nomenclature Committee of the Sixth International Pigment Cell Conference.- Biological Aspects of Pigment Cell Research.- Control of Melanophores in Amphibians.- Chemistry of the Melanocyte-stimulating Hormones.- Interrelation of the Nervous and Endocrine Factors in Regulation of Melanocytes.- Cytological and Ultrastructural Aspects of Amphibian Melanophore Control.- The Adrenocorticotrophic Hormone and Mammalian Epidermal Melanocytes.- The Influence of ACTH and MSH on Human Malignant Melanoma Cells in Vitro.- Cytological and Cytophysiological Changes in the Melanocytes of the Human Iris in Tissue Culture.- An Attempt to Isolate Melanin Granules by Gel Filtration.- A New Separation Procedure for Melatonin in Extracts.- Discussion (following papers of the first day).- The Fine Structure of Melanin Granules (the Early, Mature and Compound Forms).- Some Recent Studies on the Subcellular Unit of Melanin Biosynthesis, the Melanosome.- Correlation Between Fine Structure and Activity in Fish Melanophore.- Subcellular Tyrosinase Activity and Site of Melanogenesis in Melanocytes.- Macromolecular Characterizations in Neoplastic and Dysfunctional Human Melanocytes.- Studies on the Structure of Some Synthetic Melanins.- Investigation on the Structure of Melanin in Malignant Melanoma with 3H- and 14C-Dopa Labelled at Different Positions.- On the Chemical Nature of Urinary Melanogens.- Enzymic, Metabolic, Electron Microscopic, and Clinical Characteristics of a Human Malignant Blue Nevus.- Isoenzymes in Melanoma.- Histochemical Investigations of Melanotic Tumors.- Immunological Studies on the Transplantable Hamster Melanoma.- Discussion (following papers of the second day).- The Biology of the Malignant Melanocyte.- The Developmental Fate of Melanocytes in Murine Skin.- Comparative Aspects of the Melanoma of Grey and White Horses, a Unique Proliferative Disorder of Pigment Production.- The Tyrosine-positive Amelanotic Melanoma in the Golden Hamster.- Small Pigmented Spots in Hamsters.- Experimental Melanoma in Hamsters.- Changes in the Skin of the Syrian Hamster after a Single Application of 9,10-Dimethyl-1,2-benzanthracene.- Heterotransplantation of Experimental Melanoma.- Discussion (following papers of the third day).- Epidemiology of Malignant Melanoma in Bulgaria.- Epidemiology of Melanomas in South Africa.- Epidemiology of Melanomas in Central Asia.- Melanoblastoma in Australia.- Discussion (following papers on epidemiology).- Prognostic Factors in Malignant Melanoma.- The 32P Uptake Test in Malignant Melanoma of the Skin.- Behavior of the Thermodifference Test and the 32P Cumulative Test in the Primary Tumor and Metastasis of Melanoblastoma.- Clinical Aspects of Malignant Melanoma of the Skin.- Clinical Course of Melanoblastomas of the Skin in Children.- The Treatment of Malignant Melanoma.- Clinico-experimental Studies on Radiosensitivity of Malignant Melanoma.- Morphological Changes in Malignant Melanoma Following Contact X-ray Therapy.- Radiation and Combined Treatment of Malignant Melanoma.- Combined Treatment of Malignant Melanoma of the Skin.- Prognosis and End Results of Treatment of Cutaneous Malignant Melanoma at the Gustave Roussy Institute.- Clinical and Therapeutic Considerations on Malignant Melanoma.- End Results of Surgical Treatment of Malignant Melanoma.- Chemo-surgical Treatment of Advanced Cases of Malignant Melanoma.- Clinic on Melanoma (Panel Discussion).

Erscheint lt. Verlag 7.3.2012
Zusatzinfo XVI, 374 p.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 597 g
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Schlagworte Biology • Cancer • Cell • Cell Biology • Control • epidemiology • hormones • melanoma • Metastasis • Oncology • Regulation • Skin • Structure • therapy • tissue • Transplantation • Tumor
ISBN-10 3-642-99908-5 / 3642999085
ISBN-13 978-3-642-99908-6 / 9783642999086
Zustand Neuware
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