NMR as a Structural Tool for Macromolecules

The Theme of the Symposium.- Keynote Lecture: Intramolecular Dynamics of Biomolecules. Possibilities and Limitations of NMR.- Discussion.- Structural, Dynamic, and Folding Studies of SH2 and SH3 Domains.- Discussion.- NMR Studies of Proteins Involved in Cell Adhesion Processes.- Discussion.- Combining 2H and 13C Selective Enrichment to Probe Protein Dynamics.- Incorporating Motional Properties into the Interpretation of Three-Dimensional Solution Structures.- Discussion.- Phosphotyrosyl Peptide-Enzyme Complexes: How Much Structure Can We Get from Transferred NOE’s?.- Discussion.- Panel Discussion on Structural Refinement and Dynamics.- Recent Developments in Protein NMR Spectroscopy.- Discussion.- Field-Cycling NMR Applied to Macromolecular Structure and Dynamics.- Discussion.- Cross-Correlations: Obstacles or Tools for Structure Determination of Biomolecules.- Discussion.- Towards the Accurate Measurement of Internuclear Distances in Biological Macromolecules by Suppression of Spin Diffusion.- Discussion.- NMR of Symmetrical Assemblies of Self-Recognizing Oligonucleotides.- Discussion.- Protein-DNA Interaction from NMR and Monte Carlo Docking.- Discussion.- Dynamic Structure of Nucleic Acid Duplexes.- Discussion.- Panel Discussion on Extension of Techniques to Larger Molecules.- NMR Structures of Proteins Involved in Signal Transduction.- Discussion.- Structures of Multimeric Proteins by NMR.- Discussion.- NMR Structural Studies of Flexible Molecules.- Iron-Sulfur Proteins: Investigations of Hyperfine-Shifted Hydrogen, Carbon, and Nitrogen Resonances.- On the Use of NMR in Complex Biological Systems: NMR Studies of Calcium Sensitive Interactions amongst Muscle Proteins.- Discussion.- The Structure of Lentiviral Tat Proteins in Solution.- Discussion.- A StructuralBiologist’s View of Precision and Accuracy of Structural Models of Proteins Based on NMR Data.- Discussion.- Panel Discussion on NMR vis-à-vis Other Structural Methods.- Poster Abstracts.