Incretin Based Therapies - Sanjay Kalra, Rakesh Sahay, Ambika G Unnikrishnan

Incretin Based Therapies

Buch | Hardcover
173 Seiten
2013
Jaypee Brothers Medical Publishers (Verlag)
978-93-5025-648-0 (ISBN)
46,10 inkl. MwSt
Concise overview of incretin based therapy for the management of diabetes. Guides clinicians step by step through the history and pharmacology of various molecules.
Incretins are a group of gastrointestinal hormones that cause an increase in the amount of insulin released from cells in the pancreas after eating. Incretin based drugs are used to control blood sugar levels in the management of diabetes.



This book is a concise guide to incretin based therapy. Beginning with an introduction to the history and physiology of incretins, the following sections examine the clinical pharmacology of GLP-1 Analogues and DPP-4 Inhibitors, the pleiotrophic effects of incretins and comparative pharmacology.



Each section integrates science with practical therapeutic guidance for clinicians involved in the management of diabetes. The final chapter discusses the future of incretin therapies, including non-diabetic usage and combination therapy.



Key Features





Concise overview of incretin based therapy for the management of diabetes




Guides clinicians step by step through the history and pharmacology of various molecules
Integrates science with practical therapeutic guidance
Includes chapter on the future of incretin therapy

Sanjay Kalra MD DM Consultant Endocrinologist, Bharti Hospital, Karnal, Haryana, India Rakesh Sahay MD DNB DM FACE FICP Professor and Head, Department of Endocrinology, Osmania Medical College and Hospital, Hyderabad, Andhra Pradesh, India Ambika G Unnikrishnan MD DM MNAMS Professor, Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, Kerala, India

Section 1: Incretins: An Introduction





History of Incretins                                                                         
Physiology of Incretins                                                                   
Incretins Hormones: Effects beyond Glycemic Control               


 



Section 2: Clinical Pharmacology of GLP-1 Analogues





GLP-1 Analogues: An Overview                                                   
GLP-1 Analogues: Monotherapy                                                   
GLP-1 Analogues: Combination Therapy                                      
GLP-1 Analogues and Insulin Combination                                   


 



Section 3: Clinical Pharmacology of DPP-4 Inhibitors





DPP-4 Inhibitors: An Overview                                                      
DPP-4 Inhibitors: Monotherapy                                                     
DPP-4 Inhibitors: Combination therapy                                         


 



Section 4: Pleiotropic Effects of Incretins





Cardiovascular Effects of Incretins                                               
Neurological Effects of Incretins                                                   
Gastrointestinal and Hepatobiliary Effects of Incretins                 
Incretins and Insulin Sensitivity                                                      
Incretins and Obesity


 



Section 5: Comparative Pharmacology





GLP-1 Analogues vs. DPP-4 Inhibitors                                         
Choosing a GLP-1 Analogue                                                         
Choosing a DPP-4 Inhibitor                                                           
The Future of Incretin Therapies

Erscheint lt. Verlag 31.3.2013
Zusatzinfo 7 Illustrations, unspecified
Verlagsort New Delhi
Sprache englisch
Maße 165 x 229 mm
Themenwelt Medizinische Fachgebiete Innere Medizin Diabetologie
Medizinische Fachgebiete Innere Medizin Endokrinologie
ISBN-10 93-5025-648-7 / 9350256487
ISBN-13 978-93-5025-648-0 / 9789350256480
Zustand Neuware
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