Vitamin D and the Lung (eBook)

Mechanisms and Disease Associations

Augusto A. Litonjua (Herausgeber)

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2012 | 2012
XII, 332 Seiten
Humana Press (Verlag)
978-1-61779-888-7 (ISBN)

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Vitamin D deficiency is a worldwide problem and many associations with diseases are being discovered. Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders. Divided into three sections, the first section of the book delivers a review of how vitamin D deficiency emerged in human populations, and gives a perspective on how humans evolved to maximize the efficiency of production of vitamin D. The second section of the book reviews aspects of vitamin D mechanisms on different immune cells, lung tissue, and genetics that have potential impact on lung disease. The third section follows with chapters on associations of vitamin D with the risk for viral infections, asthma and allergies, chronic obstructive pulmonary disease, cystic fibrosis, tuberculosis, and finally, lung cancer with an emphasis on ongoing research and clinical issues and needs for future research in each field. Written by an international group of expert authors, Vitamin D and the Lung: Mechanisms and Disease Associations is an essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel.


Vitamin D deficiency is a worldwide problem and many associations with diseases are being discovered. Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders. Divided into three sections, the first section of the book delivers a review of how vitamin D deficiency emerged in human populations, and gives a perspective on how humans evolved to maximize the efficiency of production of vitamin D. The second section of the book reviews aspects of vitamin D mechanisms on different immune cells, lung tissue, and genetics that have potential impact on lung disease. The third section follows with chapters on associations of vitamin D with the risk for viral infections, asthma and allergies, chronic obstructive pulmonary disease, cystic fibrosis, tuberculosis, and finally, lung cancer with an emphasis on ongoing research and clinical issues and needs for future research in each field. Written by an international group of expert authors, Vitamin D and the Lung: Mechanisms and Disease Associations is an essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel.

Section I – Introduction                1          Vitamin D Deficiency: Historical Perspectives           Kumaravel Rajakumar                        Michael F. Holick2          Perspective: Evolution of Human Skin Color:  How Low Levels of Vitamin D Drove Natural Selection                        Scott T. Weiss Section II- Vitamin D Mechanisms of Relevance to Lung Diseases                      3          Vitamin D and Lung Development in Early Life         Virender K. Rehan                        John S. Torday4          Vitamin D and the Innate Immune Response             Philip Liu                        Aria Vazirnia5          Vitamin D and Regulatory T Cells         Catherine Hawrylowicz                        Zoe Urry                        Sarah Dimeloe6          Dendritic Cell Modulation by the Vitamin D System             Luciano Adorini                        Gilles Laverny                        Giuseppe Penna7          Vitamin D Modulates Airway Smooth Muscle Function       Audreesh Banerjee                        Reynold A. Panettieri, Jr.8          Genetic and Genomic Effects     Kelan G. Tantisira Section III. Disease Associations                        9          Acute Respiratory Infections      Jonathan M. Mansbach                        Carlos A. Camargo, Jr. 10        The role of vitamin D in the development, exacerbation, and severity of asthma and allergic diseases                        Augusto A. Litonjua11        Vitamin D and COPD         Wim Janssens                        An Lehouck

Erscheint lt. Verlag 23.5.2012
Reihe/Serie Respiratory Medicine
Respiratory Medicine
Zusatzinfo XII, 332 p.
Verlagsort Totowa
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe Diätassistenz / Ernährungsberatung
Medizin / Pharmazie Gesundheitswesen
Medizin / Pharmazie Medizinische Fachgebiete Allgemeinmedizin
Medizinische Fachgebiete Innere Medizin Pneumologie
Schlagworte Airway Smooth Muscle Cells • Asthma • COPD • Cystic fibrosis • Dendritic cells • Genetic and Genomic Effects • Innate Immune Response • Lung Cancer • Lung Development • Respiratory Epithelial Cells • T-Regulatory Cells • Tuberculosis • Viral infections • Vitamin D • Vitamin D Deficiency
ISBN-10 1-61779-888-6 / 1617798886
ISBN-13 978-1-61779-888-7 / 9781617798887
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