RNA Biochemistry and Biotechnology

1) Why RNA?.- 2) Algorithms and thermodynamics for RNA secondary structure prediction: a practical guide.- 3) Recurrent RNA motifs: Analysis at the basepair level.- 4) Towards the 3D structure of 5S rRNA.- 5) Structure and dynamics of adenosine loops in RNA bulge duplexes. RNA hydration at the bulge site.- 6) The structure and function of the ribozyme RNAse P RNA is dictated by magnesium(II) ions.- 7) Metal ion-induced cleavages in probing of RNA structure.- 8) Protein-DNA recognition.- 9) Specific interaction between damaged bases in DNA and repair enzymes.- 10) Telomeric DNA recognition.- 11) Recognition of one tRNA by two classes of aminoacyl-tRNA synthetase.- 12) Functional structures of class-I aminoacyl-tRNA synthetases.- 13) Aminoacylation of tRNA induces a conformational switch on the 3’-terminal ribose.- 14) Point mutants of elongation factor Tu from E. coli impaired in binding aminoaycl-tRNA.- 15) RNA structure and RNA-protein recognition during regulation of eukaryotic gene expression.- 16) RNA-aptamers for studying RNA protein interactions.- 17) Probing of ribonucleoprotein complexes with site-specifically derivatized RNAs.- 18) The IRE model for families of RNA structures: Selective recognition by binding proteins (IRPs), NMR spectroscopy and probing with metal coordination complexes.- 19) Functional analysis of RNA signals in the HIV-1 genome by forced evolution.- 20) Interaction of native RNAs with Tat peptides.- 21) Biogenesis, structure and function of small nucleolar RNAs.- 22) RNA structure modules with trinucleotide repeat motifs.- 23) Phosphorothioate oligonucleotides as aptamers of retroviral reverse transcriptases.- 24) Oxathiaphospholane method of the stereocontrolled synthesis of phosphorothioate analogues of oligonucleotides.- 25) Towardsimproved applications of cell-free protein biosynthesis– the influence of mRNA structure and suppressor tRNAs on the efficiency of the system.- 26) RNA on the web.- 27) How risky is direct democracy for basic science?.