Immunotherapy in Asthma
Marcel Dekker Inc (Verlag)
978-0-8247-0176-5 (ISBN)
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This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases.
Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma.
Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma
discusses the efficacy of new medications
examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies
presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses
addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults
assesses differences and similarities between intrinsic and antigen-induced asthma
describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells
explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways
reviews the genetic basis of allergy, as well as risk factors for asthma
explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies
evaluates various agents with modulatory effects on normal and pathogenic immune responses
focuses on strategies for the prevention of childhood asthma and more!
Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.
MECHANISMS OF ALLERGIC ASTHMA
Human T Helper Type 1 and Type 2 Subsets
Hans Yssel
Mechanisms of Allergic Asthma: A Th2 Disease
Douglas S. Robinson and A. Barry Kay
Mechanisms of Asthma: Asthma Is an Allergic Disease
Lisa M. Wheatley and Thomas A. E. Platts-Mills
Inflammation and Airway Remodeling in Asthma
Jean Bousquet, Pascal Chanez, Antonio M. Vignola, and Philippe Godard
The Prognosis and Natural History of Asthma
Jorrit Gerritsen, Marion H. Grol, Jan P. Schouten, and Dirkje S. Postma
ALLERGEN-SPECIFIC IMMUNOTHERAPY
Current Knowledge
Allergen Immunotherapy: Therapeutic Vaccines for Allergic Diseases (WHO Position Paper, Executive Summary)
Jean Bousquet, Richard F. Lockey, and Hans-Jørgen Malling
Allergen-Specific Immunotherapy: New Strategies Using Recombinant Allergens
Alisa M. Smith and Martin D. Chapman
Elimination of Allergens
Frédéric de Blay, François Spirlet, Martine Ott, Jean-Claude Bessot, and Gabrielle Pauli
Standardization of Allergens
Jean Bousquet and François-Bernard Michel
Allergen-Specific Immunotherapy: Past and Present
Philip S. Norman
Allergen-Specific Immunotherapy: Mechanisms of Immunotherapy
Jérôme Pène and Jean Bousquet
Objectives of Immunotherapy in Asthma
Anthony J. Frew
Allergen-Specific Immunotherapy for Asthma: Metaanalysis of Randomized Controlled Trials
Michael J. Abramson, Robert M. Puy, and John M. Weiner
Noninjective Immunotherapy: Present Knowledge and Experimental Evidence
Giovanni Passalacqua, Gian Enrico Senna, and Giorgio Walter Canonica
Pediatric Issues in Immunotherapy
Errka Valovirta
International Recommendations
Hans-Jørgen Malling
New Forms of Specific Immunotherapy
Peptide-Mediated Immunomodulation as Therapy for Allergic Disorders
Nanna S. Kristensen, Hans Yssel, and Jonathan R. Lamb
Potential of Recombinant Allergens as Immunotherapeutic Agents for Allergy and Asthma
Shyam S. Mohapatra
Molecular Characterization of Allergens, Their B-Cell Epitopes, and Allergen-Specific Antibodies for Allergy Prevention and Treatment
Rudolf Valenta, Susanne Vrtala, Tanja Ball, Sylvia Laffer, Petra Eibensteiner, Peter Steinberger, Sabine Flicker, Sabine Fischer, Irene Mittermann, Susanne Spitzauer, and Dietrich Kraft
Tolerogenic Peptides: Clinical Experience in Allergy
Christopher F. Nicodemus and George Philip
Manipulation of the Idiotypic Network: An Alternative Approach to Treat Allergic Asthma?
Yvan Boutin and Jacques Hébert
The Use of Allergen-Specific Antibodies for Immunotherapy
Jean-Marie R. Saint-Remy
REGULATION OF IgE INFLAMMATION
Immunoglobulin
Anti-Immunoglobulin E Therapy for Asthma
Pascal Demoly, Dany Jaffuel, and Jean Bousquet
Immunoglobulin Receptors
Expression and Function of the High-Affinity Receptor for Immunoglobulin E in Asthma
Marie-Hélàne Jouvin and Jean-Pierre Kinet
Factors Modulating Allergen-Induced Histamine Release: Fc-Receptors, Antibodies, and Allergens
Ronald van Ree
Regulation of Immunoglobulin E-Mediated Inflammation by Soluble Fragments of the High-Affinity Immunoglobulin E Receptor
Brian J. Sutton and Hannah J. Gould
Regulation of Immunoglobulin E Inflammation: Anti-Immunoglobulin E Autoantibodies
Beda M. Stadler, Monique Vogel, Michael P. Rudolf, Sylvia Margaret Miescher, Adrian Walter Zuercher, and Franz Kricek
NON-IMMUNOGLOBULIN E-DEPENDENT IMMUNOTHERAPY
Non-Immunoglobulin E-Dependent Immunotherapy: Treatment of Asthma with Inhaled Interferon Gamma
Gideon Lack, Donald Y. M. Leung, and Erwin W. Gelfand
Role of Interleukin-5 in Eosinophil-Based Diseases
Francis M. Cuss, Richard W. Chapman, Shelby P. Umland, Michael Minnicozzi, and Robert W. Egan
PREVENTION OF ALLERGIC ASTHMA: IS IT POSSIBLE?
Primary Prevention of Atopic Asthma: Prophylactic Strategies Based on Immunomodulation of Host Responses During Childhood
Patrick G. Holt
Outdoor Air Pollution and Asthma
Erika von Mutius
The Genetic Basis of Allergy and Asthma
Pamela J. Amelung and Eugene R. Bleecker
Gene Therapy Strategies for Asthma
Pascal Demoly, Dany Jaffuel, Jean Bousquet, Philippe Godard, and François-Bernard Michel
| Reihe/Serie | Lung Biology in Health and Disease |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 216 x 279 mm |
| Gewicht | 1043 g |
| Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie | |
| Medizinische Fachgebiete ► Innere Medizin ► Pneumologie | |
| ISBN-10 | 0-8247-0176-3 / 0824701763 |
| ISBN-13 | 978-0-8247-0176-5 / 9780824701765 |
| Zustand | Neuware |
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