Lecture Notes: Haematology

Chris S.R. Hatton is Consultant Haematologist, Department of Haematology, The John Radcliffe Hospital, Oxford Nevin C. Hughes–Jones is a Former Member of the Scientific Staff, Medical Research Council’s Molecular Immunopathology Unit, and of the Department of Pathology, University of Cambridge Deborah Hay is Wellcome Trust Clinical Training Fellow, MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford David Keeling is Consultant Haematologist, Oxford Haemophilia and Thrombosis Centre, Oxford

Preface to the first edition vi


Preface to the ninth edition vii


1 An introduction to haematopoiesis, 1


2 Anaemia: General principles, 10


3 Haemolytic anaemias, 26


4 Disorders of globin synthesis, 39


5 Conditions associated with white cell abnormalities, 51


6 Structure and function of lymphoid tissue, 59


7 Lymphomas: General principles, 65


8 Classifi cation of lymphoma, 73


9 Neoplastic disorders of lymphoid cells, 76


10 Myeloma and other paraproteinaemias, 87


11 Neoplastic disorders of myeloid cells, 93


12 Bone marrow transplantation, 104


13 Aplastic anaemia and pure red cell aplasia, 110


14 Haemostasis, abnormal bleeding and anticoagulant therapy, 114


15 Blood groups and blood transfusion, 132


16 Further reading, 143


Index, 147