Teratogenicity Testing

The ICH S5(R2) Guideline for the Testing of Medicinal Agents.-Non-Clinical Reproductive Toxicity Testing Requirements for Drugs, Pesticides, and Industrial Chemicals in India and China.-The Developmental Toxicity Testing of Biologics.-The OECD Guidelines for the Testing of Chemicals and Pesticides.-Teratology Testing Under REACH.-The Teratology Testing of Food Additives.-Developmental Toxicity Testing of Vaccines.-The Tratology Testing of Cosmetics.-Teratology Studies in the Rat.-Teratology Studies in the Mouse.-Combined Fertility and Embryotoxicity Study.-Teratology Studies in the Rabbit.-Teratology Studies in the Minipig.-Embryofetal Development Studies in Nonhuman Primates.-The Enhanced Pre- and Post-natal Development Study for Monoclonal Antibodies.-Skeletal Examination by Alizarin Staining.-Skeletal Examination by Double Staining for Ossified Bone and Cartilaginous Tissue.-Small Animal Imaging and Examination by Micro-CT.-Fetal Soft Tissue Examination by Serial Sectioning.-Fetal Soft Tissue Examinations by Microdissection.-Soft Tissue Examination Of The Fetal Rat And Rabbit Head By Magnetic Resonance Imaging.-Historical Control Data in Reproductive and Developmental Toxicity Studies.-Reporting of Teratology Studies.-Maternal Toxicity.-Innovations in Testing Strategies in Reproductive Toxicology.-Predictive Models and Computational Toxicology.-The Embryonic Stem Cell Test.-Zebrafish Teratogenicity Testing.-Frog Embryo Teratogenesis Assay on Xenopus (FETAX) and Predictivity Compared with In-vivo Mammalian Studies.-The Rat Whole Embryo Culture Assay using the Dysmorphology Score System.-Toxicogenomic Approaches in Developmental Toxicology Testing.-Validation of Alternative Tests for Developmental and Reproductive Toxicology Testing – An ILSI Health and Environmental Sciences Institute Perspective.-Regulatory Assessment of Reproductive Toxicology Data.-Hazard and Risk Assessment of Teratogenic Chemicals under REACH.-Reproductive Toxicity Risk Assessment for Pesticides.-The Thalidomide Disaster, Lessons from the Past.