Textbook of Receptor Pharmacology -

Textbook of Receptor Pharmacology

Buch | Hardcover
320 Seiten
1996
Crc Press Inc (Verlag)
978-0-8493-9227-6 (ISBN)
93,50 inkl. MwSt
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An overview of the importance of receptors in drug development, this volume reviews four major approaches to the study of receptors: molecular biology; quantitative functional studies of agonists and antagonists; ligand binding; and signal tranduction systems.
Students and researchers alike can benefit from University College London's long history of major contributions to receptor pharmacology with the Textbook of Receptor Pharmacology. This book evolved from the college's advanced receptor pharmacology course, developed by a pharmacology department that has been led by such renowned scientists as Clark, Gaddum, Schild, and Black. The text's innovative format unites four major approaches to the study of receptors: molecular biology; quantitative functional studies of agonists and antagonists; ligand binding; and signal transduction systems - a combination unprecedented in this type of book.

The Textbook of Receptor Pharmacology includes practice problems to facilitate comprehension and retention of material. It also contains helpful appendices explaining the simple mathematics used in the text. Take advantage of this comprehensive, time-saving resource on receptor pharmacology, a rapidly-expanding research area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development.

DRUG-RECEPTOR INTERACTION
Classical Approaches to the Study of Drug-Receptor Interactions, D.H. Jenkinson
MOLECULAR STRUCTURE OF RECEPTORS
Molecular Structure of G-Protein Coupled Receptors, T.W. Schwartz
Molecular Structure of Ligand-Gated Ion Channels, J. Egebjerg
Molecular Structure of Tyrosine Kinase-Linked Receptors, S. Gammeltoft and C.R. Kahn
LIGAND BINDING STUDIES OF RECEPTORS
Direct Measurement of Drug Binding to Receptors, D.G. Haylett
SIGNAL TRANSDUCTION SYSTEMS
Introduction to Signal Transduction, J.C. Foreman
Receptors Linked to Ion Channels: Activation and Block, A.J. Gibb
G-Proteins, A.C. Dolphin
Phospholipases and Phosphokinases: A Source of Lipid-Derived Second Messengers, S. Cockcroft
Intracellular Calcium, O.H. Peterson, C.C.H. Petersen, and H. Kasai
Protein Kinase C and Diacylglycerol, R. Sagi-Eisenberg
Cyclic Nucleotides, J.C. Foreman
Signal Transduction Through Protein Tyrosine Kinases, I. Kramer
RECEPTORS AS PHARMACEUTICAL TARGETS
Receptors as Pharmaceutical Targets, J.W. Black
INDEX
Some chapters include problems (and solutions) and lists for further reading.

Erscheint lt. Verlag 19.9.1996
Zusatzinfo 19 Tables, black and white
Verlagsort Bosa Roca
Sprache englisch
Maße 178 x 254 mm
Gewicht 694 g
Einbandart gebunden
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
ISBN-10 0-8493-9227-6 / 0849392276
ISBN-13 978-0-8493-9227-6 / 9780849392276
Zustand Neuware
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