Neuroblastoma (eBook)

Preface.-1. Introduction. I Diagnosis and biomarkers.-2. Pediatric cns neuroblastoma: magnetic resonance imaging and spectroscopy.-3. Pediatric neuroblastoma-associated opsoclonus-myoclonus-ataxia syndrome: early diagnosis.-4. Neuroblastoma mouse model.-5. Orbital metastasis in neuroblastoma patients.-6. Pediatric neuroblastoma: molecular detection of minimal residual disease.-7. A comprehensive tissue microarray-based fish screen of alk gene in neuroblastomas. II Therapy.-8. Neuroblastoma: triptolide therapy.-9. Neuroblastoma: ornithine decarboxylase and polyamines are novel targets for therapeutic intervention.-10. Neuroblastoma: antibody-based immunotherapy.-11. Targeting multidrug resistance in neuroblastoma.-12. Neuroblastoma: perspectives for the use of il-21 in immunotherapy.-13. Neuroblastoma: role of hypoxia and hypoxia inducible factors in tumor progression.-14. Neuroblastoma: role of gata transcription factors.-15. Neuroblastoma: role of mycn/bmil pathway in neuroblastoma.-16. Neuroblastoma: role of clusterin as a tumor suppressor gene.-17. Refractory neuroblastoma cells: statins target atp binding cassette-transporters.-18. Neuroblastoma: dosimetry for mibg therapies.-19. Advanced neuroblastoma: role of alk mutations.-20. Pediatric neuroblastoma: treatment with oral irinotecan and temozolomide. III Prognosis.-21. Genomic profiling of neuroblastoma tumors- prognostic impact of genomic aberrations.-22. Neuroblastoma patients: plasma growth factor mildkine as a prognostic growth factor.-23. Pediatric neuroblastoma: role of tgfbi (keratoepithelin).-24. Role of bone marrow infiltration detected by sensitive methods in patients with localized neuroblastoma. Index