Extracorporeal Photopheresis

Cellular Photoimmunotherapy
Buch | Hardcover
XII, 215 Seiten
2012
De Gruyter (Verlag)
978-3-11-027594-0 (ISBN)
144,95 inkl. MwSt
Extracorporeal photopheresis (ECP) is the first FDA approved cellular photoimmunotherapy for cancer, namely cutaneous T-cell lymphoma, and has demonstrated efficacy in various diseases that have a suspected involvement of pathogenic T-cells including prevention and treatment of acute and chronic graft-versus-host disease, organ transplant rejection, selected autoimmune diseases and Sezary syndrome. In ECP, patient’s blood mononuclear cells are collected, exposed to ultraviolet light in the presence of extracorporeally administered liquid 8-methoxypsoralen and reinfused. Besides its considerable efficacy ECP has an exceptional safety profile, does not cause general immunosuppression and thus, does not increase risk of infectious complications and relapse of malignant disease. Exciting preclinical data and clinical observations provide insight into the mechanisms of action of ECP and support its immunomodulatory role. This book will provide an overview on the historical development of ECP, technical aspects for its use in various patient populations including children and adults, novel research findings both in preclinical models and in various patient cohorts and will stimulate further research in organ, tissue and cell transplantation and autoimmune disorders.

Univ. Prof. Dr. Hildegard T. Greinix, Prof. Dr. Robert Knobler, both Medical University of Vienna Departments of Internal Medicine I and Dermatology Vienna, Austria.

Erscheint lt. Verlag 14.9.2012
Zusatzinfo 50 col. ill., 16 b/w tbl.
Verlagsort Berlin/Boston
Sprache englisch
Maße 170 x 240 mm
Gewicht 570 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Dermatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium Querschnittsbereiche Infektiologie / Immunologie
Schlagworte Adjuvant Therapy • Apoptosis • autoimmune disease • Autoimmune diseases • Blood • Boehme • Cancer • Cell • Clinical Medicine, other • complications • Dermatitis • Dermatology • Diseases • extrakorporale Therapie • Fetishism • Graft vs Host Disease • Immunosuppression • immunotherapy • Implant • Internist • Leukozyt • Lichttherapie • Liver • Lymphocytes • Lymphoma • Lymphoma, T-Cell, Cutaneous • Medical • Medizin • Oncology • Onkologie • Photochemotherapy • Photopherese • Photopheresis • prevention • Skin • Steroids • T ce • T Cell • therapy • Transplantation • Vaccination
ISBN-10 3-11-027594-5 / 3110275945
ISBN-13 978-3-11-027594-0 / 9783110275940
Zustand Neuware
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