Site-directed insertion of transgenes
Preface.- Section 1: Site–directed integration of transgenes.- 1 Transgene site-specific integration : troubles and solutions.- 2 : Designing non-viral targetd integrating vectors for genome enginnering in vertebrates.- 3: Gene targeting and homologous recombination in Saccharomyces cerevisiae4: Eucaryotic homologous recombination in mammalian cells.- 5 Engineered Zinc Finger Nucleases for Targeted Genome Editing .- 6: Engineered meganucleases for genome engineering purposes.- Section3: Integration based on Site-specific recombination.- 7 : Cre/loxP, Flp/FRT systems and pluripotent stem cell lines.- 8 : Site-specific recombination using C31 Integrase.- 9 : Modified transposases used for site-directed insertion of transgenes.- 10 : Targeted Plasmid Integration into the Human Genome by Engineered Recombinases.- 11: Gene site-specific insertion in plants.- 12 Site-directed insertion of transgenes in Drosophila.- 13. Nuclease Mediated Targeted Genome Modification in Mammalian Cells.- 14: Bio-applications derived from site-directed genome modification technologies.
Reihe/Serie | Topics in Current Genetics ; 23 |
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Zusatzinfo | XIV, 394 p. |
Verlagsort | Dordrecht |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Technik ► Umwelttechnik / Biotechnologie | |
Schlagworte | Transgene |
ISBN-10 | 94-007-4530-3 / 9400745303 |
ISBN-13 | 978-94-007-4530-8 / 9789400745308 |
Zustand | Neuware |
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