Targets for the Design of Antiviral Agents
Kluwer Academic/Plenum Publishers (Verlag)
978-0-306-41618-7 (ISBN)
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However, the aim of this Course was for eminent virologists to identify possible targets among the various virus classes against which the chemists could then design suitable therapeutic agents. Recent advances with antiherpesvirus drugs have shown that a far greater selectivity and therapeutic index can be obtained than was previously thought to be possible.
Overview of the Possible Targets for Viral Chemotherapy.- Viral Targets.- Herpesvirus Target Considerations for the Design of Antiviral Agents.- Picornaviruses and Togaviruses: Target for Design of Antivirals.- Targets in Negative Strand RNA Viruses (Excluding Ortho- and Paramyxoviruses.- Targets for the Design of Antiviral Agents: Targets in Orthomyxoviruses.- Biologic and Chemotherapeutic Forays into the Field of Unconventional Viruses.- Antiviral Compounds.- Anti Influenza Virus Activity of Amantadine, Rimantadine and Analogues.- Antiviral Action of 2-(?-Hydroxybenzyl)-benzimidazole (HBB).- Antirhinovirus Drugs.- Pyrimidine Nucleoside Analogues as Antiviral Agents.- Purine Nucleoside Analogs as Antiviral Agents.- Strategies in the Design of Oligonucleotides as Potential Antiviral Agents.- Oligopeptides as Specific Antiviral Agents.- Virus Associated DNA Polymerizing Activities: Their Role in Designing Antiviral and Antitumor Agents.- Conclusion.- Antiviral Agents: Why Not a "Penicillin" for Viral Infections?.- Participants.
Reihe/Serie | NATO Science Series A ; 73 |
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Zusatzinfo | 14 black & white illustrations, biography |
Sprache | englisch |
Gewicht | 870 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
ISBN-10 | 0-306-41618-2 / 0306416182 |
ISBN-13 | 978-0-306-41618-7 / 9780306416187 |
Zustand | Neuware |
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