Marine Bioprocess Engineering (eBook)
413 Seiten
Elsevier Science (Verlag)
978-0-08-053580-7 (ISBN)
Bioprocess engineering has been the key to success in the commercialization of biotechnology, especially with respect to biopharmaceuticals. In marine biotechnology, both new and existing biotechnological techniques are developed an applied to organisms from marine sources. For marine biotechnology, bioprocess engineering represents the link between discovery and commercialization. The diversity of marine life points to a myriad of new bioproducts waiting to be discovered and developed commercially.
The volume begins to bridge the gap between the isolation of products from marine organisms in the laboratory and industrial applications by focusing on the bioprocess-engineering aspects. Reviews and recent developments in product discovery, bio-energy production, cultivation of marine organisms, scale up and product recovery are presented. This publication should ensure that the engineering aspects of marine biotechnology will receive further attention in the future. Exploration of new bioproducts from the ocean should be followed up by a sustainable exploitation of these valuable resources.
This book contains full papers of both oral and poster presentations of the international symposium 'Marine Bioprocess Engineering' which was held in Noordwijkerhout, The Netherlands, 1998. The symposium focused on the bioprocessing of marine natural products.Bioprocess engineering has been the key to success in the commercialization of biotechnology, especially with respect to biopharmaceuticals. In marine biotechnology, both new and existing biotechnological techniques are developed an applied to organisms from marine sources. For marine biotechnology, bioprocess engineering represents the link between discovery and commercialization.The diversity of marine life points to a myriad of new bioproducts waiting to be discovered and developed commercially.The volume begins to bridge the gap between the isolation of products from marine organisms in the laboratory and industrial applications by focusing on the bioprocess-engineering aspects. Reviews and recent developments in product discovery, bio-energy production, cultivation of marine organisms, scale up and product recovery are presented.This publication should ensure that the engineering aspects of marine biotechnology will receive further attention in the future. Exploration of new bioproducts from the ocean should be followed up by a sustainable exploitation of these valuable resources.
Cover 1
Contents 8
Editorial 12
Part I: Opening keynote 16
Chapter 1.The bioprocess-technological potential of the sea 16
Part II: Products 26
Chapter 2. The discovery and development of marine compounds with pharmaceutical potential 26
Chapter 3. Microbial antagonism: a neglected avenue of natural products research 38
Chapter 4. Screening of marine microalgae for bioremediation of cadmium-polluted seawater 44
Chapter 5. Diatom silicon biomineralization as an inspirational source of new approaches to silica production 50
Chapter 6. Biosynthesis and properties of an extracellular metalloprotease from the Antarctic marine bacterium Sphingomonas paucimobilis 64
Chapter 7. Cyanobacteria„a potential source of new biologically active substances 72
Chapter 8. Biodiversity and potentials of marine-derived microorganisms 76
Chapter 9. Production and particle characterization of the frustules of Cyclotella cryptica in comparison with siliceous earth 82
Chapter 10. Biotechnological potential of North Sea salt marsh plants„a review of traditional knowledge 88
Chapter 11. The pharmaceutical exploration of cold water ascidians from the Netherlands: a possible source of new cytotoxic natural products 96
Part III: Energy 100
Chapter 12. Biotechnological hydrogen production: research for efficient light energy conversion 100
Chapter 13. Substrate consumption rates for hydrogen production by Rhodobacter sphaeroides in a column photobioreactor 114
Chapter 14. The biocatalytic effect of Halobacterium halobium on photoelectrochemical hydrogen production 126
Chapter 15. Identification of by-products in hydrogen producing bacteria Rhodobacter sphaeroides O.U. 001 grown in the waste water of a sugar refinery
Part IV: Cultivation of marine organisms 144
Chapter 16. Cell cultures from marine invertebrates: obstacles, new approaches and recent improvements 144
Chapter 17. Growth of the sponge Pseudosuberites (aff.) andrewsi in a closed system 166
Chapter 18. Aquaculture of sponges on scallops for natural products research and antifouling 174
Chapter 19. Photoheterotrophy in the production of phytoplankton organisms 186
Chapter 20. Optimisation of docosahexaenoic acid production in batch cultivations by Crypthecodinium cohnii 196
Chapter 21. Long-chain n„3 polyunsaturated fatty acid production by members of the marine protistan group the thraustochytrids: screening of isolates and optimisation of docosahexaenoic acid production 204
Chapter 22. Cultivation of the marine basidiomycete Nia vibrissa (Moore & Meyers)
Chapter 23. Controlled cultivation of Alexandrium minutum and [33p] orthophosphate cell labeling towards surface adhesion tests 218
Chapter 24. Production of a-tocopherol by sequential heterotrophic–photoautotrophic cultivation of Euglena gracilis 224
Chapter 25. Effect of Ca2+ channel blockers on glycerol levels in Dunaliella tertiolecta under hypoosmotic stress 234
Chapter 26. Sporulation and sterilization method for axenic culture of Gelidium canariensis 238
Part V: Design and scale-up of in vitro cultures 242
Chapter 27. Photobioreactors: light regime, mass transfer, and scaleup 242
Chapter 28. Comparative evaluation of compact photobioreactors for large-scale monoculture of microalgae 260
Chapter 29. Outdoor continuous culture of Porphyridium cruentum in a tubular photobioreactor: quantitative analysis of the daily cyclic variation of culture parameters 282
Chapter 30. An integrated solar and artificial light system for internal illumination of photobioreactors 300
Chapter 31. Production of eicosapentaenoic acid by Nannochloropsis sp. cultures in outdoor tubular photobioreactors 310
Chapter 32. Commercial production of microalgae: ponds, tanks, tubes and fermenters 324
Chapter 33. Specific growth rate of Chlamydomonas reinhardtii and Chlorella sorokiniana under medium duration light/dark cycles: 13–87 s 334
Chapter 34. Modelling of a continuous pilot photobioreactor for microalgae production 346
Chapter 35. Opportunities for marine bioprocess intensification using novel bioreactor design: frequency of barotolerance in microorganisms obtained from surface waters 354
Chapter 36. Effect of light-path length in outdoor flat plate reactors on output rate of cell mass and of EPA in Nannochloropsis sp. 362
Chapter 37. Methanol as alternative carbon source for quicker efficient production of the microalgae Chlorella minutissima: Role of the concentration and frequence of administration 368
Part VI: Product recovery 374
Chapter 38. Fishing products from the sea–rational downstream processing of marine bioproducts 374
Chapter 39. The preparation and applications of functional fibres from crab shell chitin 384
Chapter 40. Lipase-catalyzed esterification of glycerol and polyunsaturated fatty acids from fish and microalgae oils 390
Chapter 41. Concentration and desalting by membrane processes of a natural pigment produced by the marine diatom Haslea ostrearia Simonsen 404
Part VII: Closing keynote 414
Chapter 42. Marine bioprocess engineering: the missing link to commercialization 414
Author Index 420
Subject Index 424
Erscheint lt. Verlag | 19.11.1999 |
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Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
Medizin / Pharmazie ► Medizinische Fachgebiete | |
Naturwissenschaften ► Biologie ► Limnologie / Meeresbiologie | |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Naturwissenschaften ► Geowissenschaften ► Hydrologie / Ozeanografie | |
Technik ► Umwelttechnik / Biotechnologie | |
ISBN-10 | 0-08-053580-1 / 0080535801 |
ISBN-13 | 978-0-08-053580-7 / 9780080535807 |
Haben Sie eine Frage zum Produkt? |
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